UU-Mamba: Uncertainty-aware U-Mamba for Cardiac Image Segmentation

Fuente: arXiv
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Main Authors: Tsai, Ting Yu, Lin, Li, Hu, Shu, Chang, Ming-Ching, Zhu, Hongtu, Wang, Xin
Format: Preprint
Published: 2024
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author Tsai, Ting Yu
Lin, Li
Hu, Shu
Chang, Ming-Ching
Zhu, Hongtu
Wang, Xin
author_facet Tsai, Ting Yu
Lin, Li
Hu, Shu
Chang, Ming-Ching
Zhu, Hongtu
Wang, Xin
contents Biomedical image segmentation is critical for accurate identification and analysis of anatomical structures in medical imaging, particularly in cardiac MRI. Manual segmentation is labor-intensive, time-consuming, and prone to errors, highlighting the need for automated methods. However, current machine learning approaches face challenges like overfitting and data demands. To tackle these issues, we propose a new UU-Mamba model, integrating the U-Mamba model with the Sharpness-Aware Minimization (SAM) optimizer and an uncertainty-aware loss function. SAM enhances generalization by locating flat minima in the loss landscape, thus reducing overfitting. The uncertainty-aware loss combines region-based, distribution-based, and pixel-based loss designs to improve segmentation accuracy and robustness. Evaluation of our method is performed on the ACDC cardiac dataset, outperforming state-of-the-art models including TransUNet, Swin-Unet, nnUNet, and nnFormer. Our approach achieves Dice Similarity Coefficient (DSC) and Mean Squared Error (MSE) scores, demonstrating its effectiveness in cardiac MRI segmentation.
format Preprint
id arxiv_https___arxiv_org_abs_2405_17496
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle UU-Mamba: Uncertainty-aware U-Mamba for Cardiac Image Segmentation
Tsai, Ting Yu
Lin, Li
Hu, Shu
Chang, Ming-Ching
Zhu, Hongtu
Wang, Xin
Image and Video Processing
Biomedical image segmentation is critical for accurate identification and analysis of anatomical structures in medical imaging, particularly in cardiac MRI. Manual segmentation is labor-intensive, time-consuming, and prone to errors, highlighting the need for automated methods. However, current machine learning approaches face challenges like overfitting and data demands. To tackle these issues, we propose a new UU-Mamba model, integrating the U-Mamba model with the Sharpness-Aware Minimization (SAM) optimizer and an uncertainty-aware loss function. SAM enhances generalization by locating flat minima in the loss landscape, thus reducing overfitting. The uncertainty-aware loss combines region-based, distribution-based, and pixel-based loss designs to improve segmentation accuracy and robustness. Evaluation of our method is performed on the ACDC cardiac dataset, outperforming state-of-the-art models including TransUNet, Swin-Unet, nnUNet, and nnFormer. Our approach achieves Dice Similarity Coefficient (DSC) and Mean Squared Error (MSE) scores, demonstrating its effectiveness in cardiac MRI segmentation.
title UU-Mamba: Uncertainty-aware U-Mamba for Cardiac Image Segmentation
topic Image and Video Processing
url https://arxiv.org/abs/2405.17496