Dr-LLaVA: Visual Instruction Tuning with Symbolic Clinical Grounding

Fuente: arXiv
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Autori principali: Sun, Shenghuan, Schubert, Alexander, Goldgof, Gregory M., Sun, Zhiqing, Hartvigsen, Thomas, Butte, Atul J., Alaa, Ahmed
Natura: Preprint
Pubblicazione: 2024
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author Sun, Shenghuan
Schubert, Alexander
Goldgof, Gregory M.
Sun, Zhiqing
Hartvigsen, Thomas
Butte, Atul J.
Alaa, Ahmed
author_facet Sun, Shenghuan
Schubert, Alexander
Goldgof, Gregory M.
Sun, Zhiqing
Hartvigsen, Thomas
Butte, Atul J.
Alaa, Ahmed
contents Vision-Language Models (VLM) can support clinicians by analyzing medical images and engaging in natural language interactions to assist in diagnostic and treatment tasks. However, VLMs often exhibit "hallucinogenic" behavior, generating textual outputs not grounded in contextual multimodal information. This challenge is particularly pronounced in the medical domain, where we do not only require VLM outputs to be accurate in single interactions but also to be consistent with clinical reasoning and diagnostic pathways throughout multi-turn conversations. For this purpose, we propose a new alignment algorithm that uses symbolic representations of clinical reasoning to ground VLMs in medical knowledge. These representations are utilized to (i) generate GPT-4-guided visual instruction tuning data at scale, simulating clinician-VLM conversations with demonstrations of clinical reasoning, and (ii) create an automatic reward function that evaluates the clinical validity of VLM generations throughout clinician-VLM interactions. Our algorithm eliminates the need for human involvement in training data generation or reward model construction, reducing costs compared to standard reinforcement learning with human feedback (RLHF). We apply our alignment algorithm to develop Dr-LLaVA, a conversational VLM finetuned for analyzing bone marrow pathology slides, demonstrating strong performance in multi-turn medical conversations.
format Preprint
id arxiv_https___arxiv_org_abs_2405_19567
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Dr-LLaVA: Visual Instruction Tuning with Symbolic Clinical Grounding
Sun, Shenghuan
Schubert, Alexander
Goldgof, Gregory M.
Sun, Zhiqing
Hartvigsen, Thomas
Butte, Atul J.
Alaa, Ahmed
Artificial Intelligence
Computation and Language
Computer Vision and Pattern Recognition
Machine Learning
Vision-Language Models (VLM) can support clinicians by analyzing medical images and engaging in natural language interactions to assist in diagnostic and treatment tasks. However, VLMs often exhibit "hallucinogenic" behavior, generating textual outputs not grounded in contextual multimodal information. This challenge is particularly pronounced in the medical domain, where we do not only require VLM outputs to be accurate in single interactions but also to be consistent with clinical reasoning and diagnostic pathways throughout multi-turn conversations. For this purpose, we propose a new alignment algorithm that uses symbolic representations of clinical reasoning to ground VLMs in medical knowledge. These representations are utilized to (i) generate GPT-4-guided visual instruction tuning data at scale, simulating clinician-VLM conversations with demonstrations of clinical reasoning, and (ii) create an automatic reward function that evaluates the clinical validity of VLM generations throughout clinician-VLM interactions. Our algorithm eliminates the need for human involvement in training data generation or reward model construction, reducing costs compared to standard reinforcement learning with human feedback (RLHF). We apply our alignment algorithm to develop Dr-LLaVA, a conversational VLM finetuned for analyzing bone marrow pathology slides, demonstrating strong performance in multi-turn medical conversations.
title Dr-LLaVA: Visual Instruction Tuning with Symbolic Clinical Grounding
topic Artificial Intelligence
Computation and Language
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2405.19567