Detection of Acetone as a Gas Biomarker for Diabetes Based on Gas Sensor Technology

Fuente: arXiv
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Autores principales: Wei, Jiaming, Liu, Tong, Huang, Jipeng, Li, Xiaowei, Qi, Yurui, Luo, Gangyin
Formato: Preprint
Publicado: 2024
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author Wei, Jiaming
Liu, Tong
Huang, Jipeng
Li, Xiaowei
Qi, Yurui
Luo, Gangyin
author_facet Wei, Jiaming
Liu, Tong
Huang, Jipeng
Li, Xiaowei
Qi, Yurui
Luo, Gangyin
contents With the continuous development and improvement of medical services, there is a growing demand for improving diabetes diagnosis. Exhaled breath analysis, characterized by its speed, convenience, and non-invasive nature, is leading the trend in diagnostic development. Studies have shown that the acetone levels in the breath of diabetes patients are higher than normal, making acetone a basis for diabetes breath analysis. This provides a more readily accepted method for early diabetes prevention and monitoring. Addressing issues such as the invasive nature, disease transmission risks, and complexity of diabetes testing, this study aims to design a diabetes gas biomarker acetone detection system centered around a sensor array using gas sensors and pattern recognition algorithms. The research covers sensor selection, sensor preparation, circuit design, data acquisition and processing, and detection model establishment to accurately identify acetone. Titanium dioxide was chosen as the nano gas-sensitive material to prepare the acetone gas sensor, with data collection conducted using STM32. Filtering was applied to process the raw sensor data, followed by feature extraction using principal component analysis. A recognition model based on support vector machine algorithm was used for qualitative identification of gas samples, while a recognition model based on backpropagation neural network was employed for quantitative detection of gas sample concentrations. Experimental results demonstrated recognition accuracies of 96% and 97.5% for acetone-ethanol and acetone-methanol mixed gases, and 90% for ternary acetone, ethanol, and methanol mixed gases.
format Preprint
id arxiv_https___arxiv_org_abs_2406_00993
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Detection of Acetone as a Gas Biomarker for Diabetes Based on Gas Sensor Technology
Wei, Jiaming
Liu, Tong
Huang, Jipeng
Li, Xiaowei
Qi, Yurui
Luo, Gangyin
Signal Processing
Human-Computer Interaction
Other Quantitative Biology
With the continuous development and improvement of medical services, there is a growing demand for improving diabetes diagnosis. Exhaled breath analysis, characterized by its speed, convenience, and non-invasive nature, is leading the trend in diagnostic development. Studies have shown that the acetone levels in the breath of diabetes patients are higher than normal, making acetone a basis for diabetes breath analysis. This provides a more readily accepted method for early diabetes prevention and monitoring. Addressing issues such as the invasive nature, disease transmission risks, and complexity of diabetes testing, this study aims to design a diabetes gas biomarker acetone detection system centered around a sensor array using gas sensors and pattern recognition algorithms. The research covers sensor selection, sensor preparation, circuit design, data acquisition and processing, and detection model establishment to accurately identify acetone. Titanium dioxide was chosen as the nano gas-sensitive material to prepare the acetone gas sensor, with data collection conducted using STM32. Filtering was applied to process the raw sensor data, followed by feature extraction using principal component analysis. A recognition model based on support vector machine algorithm was used for qualitative identification of gas samples, while a recognition model based on backpropagation neural network was employed for quantitative detection of gas sample concentrations. Experimental results demonstrated recognition accuracies of 96% and 97.5% for acetone-ethanol and acetone-methanol mixed gases, and 90% for ternary acetone, ethanol, and methanol mixed gases.
title Detection of Acetone as a Gas Biomarker for Diabetes Based on Gas Sensor Technology
topic Signal Processing
Human-Computer Interaction
Other Quantitative Biology
url https://arxiv.org/abs/2406.00993