Conductivity and Electrode Placement Variability: Evaluating the Cramer-Rao Lower Bound in 2D Electrical Impedance Tomography

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Auteurs principaux: Kormakov, Georgii, Koshev, Nikolay
Format: Preprint
Publié: 2024
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author Kormakov, Georgii
Koshev, Nikolay
author_facet Kormakov, Georgii
Koshev, Nikolay
contents Electrical Impedance Tomography (EIT) is a non-invasive imaging modality that has earned significant attention for its potential in real-time monitoring of various physiological parameters. Despite its promise, the sensitivity and resolution of EIT remain areas of active research. This article presents a new way to analyse the sensitivity of EIT systems using the Cramer-Rao Lower Bound (CRLB). This statistical tool provides a theoretical lower bound on the variance of unbiased estimators. To simulate the EIT full cycle, we compared two forward models: standard Dirichlet-to-Neumann (DtN) and restricted DtN. By taking the CRLB over modelled with Finite Elements Method (FEM) 2D circular area with various conductivity patterns, we showed the influence of electrode configuration on each basic FEM element sensitivity. Also, the sensitivity on small perturbations for different conductivity patterns was offered. This article aims to bridge the gap between the research of widely used hardware implementations standard forward DtN model and theoretically approved restricted DtN. We conclude with a discussion on the motivation behind this research and the objectives our work introduces for the inverse restricted DtN model in practice.
format Preprint
id arxiv_https___arxiv_org_abs_2406_02570
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Conductivity and Electrode Placement Variability: Evaluating the Cramer-Rao Lower Bound in 2D Electrical Impedance Tomography
Kormakov, Georgii
Koshev, Nikolay
Medical Physics
Electrical Impedance Tomography (EIT) is a non-invasive imaging modality that has earned significant attention for its potential in real-time monitoring of various physiological parameters. Despite its promise, the sensitivity and resolution of EIT remain areas of active research. This article presents a new way to analyse the sensitivity of EIT systems using the Cramer-Rao Lower Bound (CRLB). This statistical tool provides a theoretical lower bound on the variance of unbiased estimators. To simulate the EIT full cycle, we compared two forward models: standard Dirichlet-to-Neumann (DtN) and restricted DtN. By taking the CRLB over modelled with Finite Elements Method (FEM) 2D circular area with various conductivity patterns, we showed the influence of electrode configuration on each basic FEM element sensitivity. Also, the sensitivity on small perturbations for different conductivity patterns was offered. This article aims to bridge the gap between the research of widely used hardware implementations standard forward DtN model and theoretically approved restricted DtN. We conclude with a discussion on the motivation behind this research and the objectives our work introduces for the inverse restricted DtN model in practice.
title Conductivity and Electrode Placement Variability: Evaluating the Cramer-Rao Lower Bound in 2D Electrical Impedance Tomography
topic Medical Physics
url https://arxiv.org/abs/2406.02570