Chemically Regulated Conical Channel Synapse for Neuromorphic and Sensing Applications

Fuente: arXiv
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Autores principales: Kamsma, T. M., Klop, M. S., Boon, W. Q., Spitoni, C., Rueckauer, B., van Roij, R.
Formato: Preprint
Publicado: 2024
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author Kamsma, T. M.
Klop, M. S.
Boon, W. Q.
Spitoni, C.
Rueckauer, B.
van Roij, R.
author_facet Kamsma, T. M.
Klop, M. S.
Boon, W. Q.
Spitoni, C.
Rueckauer, B.
van Roij, R.
contents Fluidic iontronics offer a unique capability for emulating the chemical processes found in neurons. We extract multiple distinct chemically regulated synaptic features from an experimentally accessible conical microfluidic channel carrying functionalized surface groups, using finite-element calculations of continuum transport equations. By modeling a Langmuir-type surface reaction on the channel wall we couple fast voltage-induced volumetric salt accumulation with a long-term channel surface charge modulation by means of fast charging and slow discharging. These nonlinear charging dynamics emerge across several orders of magnitude of reaction rates and equilibria, and are understood through an analytic approximation rooted in first-principles. We show how short-and long-term potentiation and depression, frequency-dependent plasticity, and chemical-electrical signal spike-timing dependence and coincidence detection (acting like a chemical-electrical AND logic gate), akin to the NMDA mechanism for Hebbian learning in biological synapses, can all be emulated.
format Preprint
id arxiv_https___arxiv_org_abs_2406_03195
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Chemically Regulated Conical Channel Synapse for Neuromorphic and Sensing Applications
Kamsma, T. M.
Klop, M. S.
Boon, W. Q.
Spitoni, C.
Rueckauer, B.
van Roij, R.
Soft Condensed Matter
Fluidic iontronics offer a unique capability for emulating the chemical processes found in neurons. We extract multiple distinct chemically regulated synaptic features from an experimentally accessible conical microfluidic channel carrying functionalized surface groups, using finite-element calculations of continuum transport equations. By modeling a Langmuir-type surface reaction on the channel wall we couple fast voltage-induced volumetric salt accumulation with a long-term channel surface charge modulation by means of fast charging and slow discharging. These nonlinear charging dynamics emerge across several orders of magnitude of reaction rates and equilibria, and are understood through an analytic approximation rooted in first-principles. We show how short-and long-term potentiation and depression, frequency-dependent plasticity, and chemical-electrical signal spike-timing dependence and coincidence detection (acting like a chemical-electrical AND logic gate), akin to the NMDA mechanism for Hebbian learning in biological synapses, can all be emulated.
title Chemically Regulated Conical Channel Synapse for Neuromorphic and Sensing Applications
topic Soft Condensed Matter
url https://arxiv.org/abs/2406.03195