Hibou: A Family of Foundational Vision Transformers for Pathology

Fuente: arXiv
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Auteurs principaux: Nechaev, Dmitry, Pchelnikov, Alexey, Ivanova, Ekaterina
Format: Preprint
Publié: 2024
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author Nechaev, Dmitry
Pchelnikov, Alexey
Ivanova, Ekaterina
author_facet Nechaev, Dmitry
Pchelnikov, Alexey
Ivanova, Ekaterina
contents Pathology, the microscopic examination of diseased tissue, is critical for diagnosing various medical conditions, particularly cancers. Traditional methods are labor-intensive and prone to human error. Digital pathology, which converts glass slides into high-resolution digital images for analysis by computer algorithms, revolutionizes the field by enhancing diagnostic accuracy, consistency, and efficiency through automated image analysis and large-scale data processing. Foundational transformer pretraining is crucial for developing robust, generalizable models as it enables learning from vast amounts of unannotated data. This paper introduces the Hibou family of foundational vision transformers for pathology, leveraging the DINOv2 framework to pretrain two model variants, Hibou-B and Hibou-L, on a proprietary dataset of over 1 million whole slide images (WSIs) representing diverse tissue types and staining techniques. Our pretrained models demonstrate superior performance on both patch-level and slide-level benchmarks, surpassing existing state-of-the-art methods. Notably, Hibou-L achieves the highest average accuracy across multiple benchmark datasets. To support further research and application in the field, we have open-sourced the Hibou models, which can be accessed at https://github.com/HistAI/hibou.
format Preprint
id arxiv_https___arxiv_org_abs_2406_05074
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Hibou: A Family of Foundational Vision Transformers for Pathology
Nechaev, Dmitry
Pchelnikov, Alexey
Ivanova, Ekaterina
Image and Video Processing
Computer Vision and Pattern Recognition
Pathology, the microscopic examination of diseased tissue, is critical for diagnosing various medical conditions, particularly cancers. Traditional methods are labor-intensive and prone to human error. Digital pathology, which converts glass slides into high-resolution digital images for analysis by computer algorithms, revolutionizes the field by enhancing diagnostic accuracy, consistency, and efficiency through automated image analysis and large-scale data processing. Foundational transformer pretraining is crucial for developing robust, generalizable models as it enables learning from vast amounts of unannotated data. This paper introduces the Hibou family of foundational vision transformers for pathology, leveraging the DINOv2 framework to pretrain two model variants, Hibou-B and Hibou-L, on a proprietary dataset of over 1 million whole slide images (WSIs) representing diverse tissue types and staining techniques. Our pretrained models demonstrate superior performance on both patch-level and slide-level benchmarks, surpassing existing state-of-the-art methods. Notably, Hibou-L achieves the highest average accuracy across multiple benchmark datasets. To support further research and application in the field, we have open-sourced the Hibou models, which can be accessed at https://github.com/HistAI/hibou.
title Hibou: A Family of Foundational Vision Transformers for Pathology
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2406.05074