Image de couverture de livre

Biomarker-Guided Adaptive Enrichment Design with Threshold Detection for Clinical Trials with Time-to-Event Outcome

Fuente: arXiv

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Hua, Kaiyuan, Hong, Hwanhee, Wang, Xiaofei
Format:	Preprint
Publié:	2024
Sujets:	Methodology
Accès en ligne:	Acceder al recurso
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Inference of treatment effect and its regional modifiers using restricted mean survival time in multi-regional clinical trials
par: Hua, Kaiyuan, et autres
Publié: (2024)

Network Meta‐Analysis of Time‐to‐Event Endpoints With Individual Participant Data Using Restricted Mean Survival Time Regression
par: Kaiyuan Hua, et autres
Publié: (2025)

Integrating Randomized Controlled Trial and External Control Data Using Balancing Weights: A Comparison of Estimands and Estimators
par: Wang, Peijin, et autres
Publié: (2025)

Data-Adaptive and Model-Robust Covariate Adjustment for Time-to-Event Outcomes in Stratified Randomized Trials
par: Kim, Raphael C., et autres
Publié: (2026)

Bayesian hierarchical models with calibrated mixtures of g-priors for assessing treatment effect moderation in meta-analysis
par: Wang, Qiao, et autres
Publié: (2024)

Network Meta‐Analysis With Individual Participant‐Level Data of Time‐to‐Event Outcomes Using Cox Regression
par: Kaiyuan Hua, et autres
Publié: (2025)

Restricted Win Probability with Bayesian Estimation for Implementing the Estimand Framework in Clinical Trials With a Time-to-Event Outcome
par: Leeberg, Michelle, et autres
Publié: (2024)

Prediction Intervals for Interim Events in Randomized Clinical Trials with Time-to-Event Endpoints
par: Ratti, Edoardo, et autres
Publié: (2026)

Inference for Cumulative Incidences and Treatment Effects in Randomized Controlled Trials with Time-to-Event Outcomes under ICH E9 (R1)
par: Deng, Yuhao, et autres
Publié: (2024)

Fragility Index for Time-to-Event Endpoints in Single-Arm Clinical Trials
par: Maity, Arnab Kumar, et autres
Publié: (2024)

Study Duration Prediction for Clinical Trials with Time-to-Event Endpoints Using Mixture Distributions Accounting for Heterogeneous Population
par: Zhang, Hong, et autres
Publié: (2023)

Robust Estimation and Inference in Hybrid Controlled Trials for Binary Outcomes: A Case Study on Non-Small Cell Lung Cancer
par: Liu, Jiajun, et autres
Publié: (2025)

Beyond Fixed Restriction Time: Adaptive Restricted Mean Survival Time Methods in Clinical Trials
par: Sun, Jinghao, et autres
Publié: (2025)

Statistical Design and Planning of an Adaptive Trial using Hierarchical Composite Outcomes: A Practical example
par: Padmanabhan, Krishna, et autres
Publié: (2025)

Selective Information Borrowing for Region-Specific Treatment Effect Inference under Covariate Mismatch in Multi-Regional Clinical Trials
par: Li, Chenxi, et autres
Publié: (2026)

A Two-Step Test to Identify Zero-Inflated Biomarkers in Early-Phase Clinical Trials
par: Xi, Nan Miles, et autres
Publié: (2025)

Identifying Treatment Effect Heterogeneity with Bayesian Hierarchical Adjustable Random Partition in Adaptive Enrichment Trials
par: Zhao, Xianglin, et autres
Publié: (2025)

Statistical Inference for Heterogeneous Treatment Effect with Right-censored Data from Synthesizing Randomized Clinical Trials and Real-world Data
par: Mao, Guangcai, et autres
Publié: (2025)

Conditional Inference for Secondary Outcomes Based on the Testing Result for the Primary Outcome in Clinical Trials
par: Pan, Tianyu, et autres
Publié: (2025)

Leveraging External Data for Testing Experimental Therapies with Biomarker Interactions in Randomized Clinical Trials
par: Ren, Boyu, et autres
Publié: (2025)

Design of Bayesian Clinical Trials with Clustered Data
par: Hagar, Luke, et autres
Publié: (2025)

The Win Ratio at the Design Stage of Clinical Trials
par: Kronthaler, David, et autres
Publié: (2025)

Covariate-Adjusted Response-Adaptive Design with Delayed Outcomes
par: Ma, Xinwei, et autres
Publié: (2025)

History-Aware Conformal Prediction Sets for Censored Time-to-Event Outcomes
par: Wang, Yuyao, et autres
Publié: (2026)

BMW: Bayesian Model-Assisted Adaptive Phase II Clinical Trial Design for Win Ratio Statistic
par: Zhu, Di, et autres
Publié: (2026)

Optimal Adaptive SMART Designs with Binary Outcomes
par: Ghosh, Rik, et autres
Publié: (2023)

Enhancing Statistical Validity and Power in Hybrid Controlled Trials: A Randomization Inference Approach with Conformal Selective Borrowing
par: Zhu, Ke, et autres
Publié: (2024)

Heterogeneous Clinical Trial Outcomes via Multi-Output Gaussian Processes
par: Thomas, Owen, et autres
Publié: (2024)

TITE-Safety: Time-to-event Safety Monitoring for Clinical Trials
par: Martens, Michael J., et autres
Publié: (2025)

Two-stage Adaptive Design Cluster Randomised Trials
par: Watson, Samuel I., et autres
Publié: (2026)

SIMBA -- A Bayesian Decision Framework for the Identification of Optimal Biomarker Subgroups for Cancer Basket Clinical Trials
par: Yuan, Shijie, et autres
Publié: (2025)

E-values for Adaptive Clinical Trials: Anytime-Valid Monitoring in Practice
par: Sokolova, Alexandra, et autres
Publié: (2026)

A Unified Inference Method for FROC-type Curves and Related Summary Indices
par: Sun, Jiarui, et autres
Publié: (2025)

Simplifying Causal Mediation Analysis for Time-to-Event Outcomes using Pseudo-Values
par: Ocampo, Alex, et autres
Publié: (2024)

Minimax Optimal Robust Sparse Regression with Heavy-Tailed Designs: A Gradient-Based Approach
par: Zhou, Kaiyuan, et autres
Publié: (2026)

An Adaptive Phase II Trial Design for Dose Selection and Addition in Microfilarial Infections
par: Zehetmayer, Sonja, et autres
Publié: (2026)

Improving Power in Randomized Controlled Trials with Time-to-Event Endpoints: A Risk-Free Approach
par: Zhou, Junyi, et autres
Publié: (2026)

Adaptive CUSUM Chart for Real-Time Monitoring of Bivariate Event Data
par: Parakulum, Gokul, et autres
Publié: (2025)

Dynamic Prediction of the Target Survival Time in Metastatic Solid Tumor Cancer Clinical Trials
par: Wang, Sidi, et autres
Publié: (2026)

Data-Adaptive Automatic Threshold Calibration for Stability Selection
par: Huang, Martin, et autres
Publié: (2025)