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Main Authors: He, Xinyi, Wang, Shidi, Li, Yi, Wang, Jiucun, Yang, Guangrui, Chen, Jun, Hu, Zixin
Format: Preprint
Published: 2024
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Online Access:https://arxiv.org/abs/2406.13284
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author He, Xinyi
Wang, Shidi
Li, Yi
Wang, Jiucun
Yang, Guangrui
Chen, Jun
Hu, Zixin
author_facet He, Xinyi
Wang, Shidi
Li, Yi
Wang, Jiucun
Yang, Guangrui
Chen, Jun
Hu, Zixin
contents Background The incidence of stroke places a heavy burden on both society and individuals. Activity is closely related to cardiovascular health. This study aimed to investigate the relationship between the varying domains of PA, like occupation-related Physical Activity (OPA), transportation-related Physical Activity (TPA), leisure-time Physical Activity (LTPA), and Sedentary Activity (SA) with stroke. Methods Our analysis included 30,400 participants aged 20+ years from 2007 to 2018 National Health and Nutrition Examination Survey (NHANES). Stroke was identified based on the participant's self-reported diagnoses from previous medical consultations, and PA and SA were self-reported. Multivariable logistic and restricted cubic spline models were used to assess the associations. Results Participants achieving PA guidelines (performing PA more than 150 min/week) were 35.7% less likely to have a stroke based on both the total PA (odds ratio [OR] 0.643, 95% confidence interval [CI] 0.523-0.790) and LTPA (OR 0.643, 95% CI 0.514-0.805), while OPA or TPA did not demonstrate lower stroke risk. Furthermore, participants with less than 7.5 h/day SA levels were 21.6% (OR 0.784, 95% CI 0.665-0.925) less likely to have a stroke. The intensities of total PA and LTPA exhibited nonlinear U-shaped associations with stroke risk. In contrast, those of OPA and TPA showed negative linear associations, while SA intensities were positively linearly correlated with stroke risk. Conclusions LTPA, but not OPA or TPA, was associated with a lower risk of stroke at any amount, suggesting that significant cardiovascular health would benefit from increased PA. Additionally, the positive association between SA and stroke indicated that prolonged sitting was detrimental to cardiovascular health. Overall, increased PA within a reasonable range reduces the risk of stroke, while increased SA elevates it.
format Preprint
id arxiv_https___arxiv_org_abs_2406_13284
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle The association of domain-specific physical activity and sedentary activity with stroke: A prospective cohort study
He, Xinyi
Wang, Shidi
Li, Yi
Wang, Jiucun
Yang, Guangrui
Chen, Jun
Hu, Zixin
Medical Physics
Quantitative Methods
Background The incidence of stroke places a heavy burden on both society and individuals. Activity is closely related to cardiovascular health. This study aimed to investigate the relationship between the varying domains of PA, like occupation-related Physical Activity (OPA), transportation-related Physical Activity (TPA), leisure-time Physical Activity (LTPA), and Sedentary Activity (SA) with stroke. Methods Our analysis included 30,400 participants aged 20+ years from 2007 to 2018 National Health and Nutrition Examination Survey (NHANES). Stroke was identified based on the participant's self-reported diagnoses from previous medical consultations, and PA and SA were self-reported. Multivariable logistic and restricted cubic spline models were used to assess the associations. Results Participants achieving PA guidelines (performing PA more than 150 min/week) were 35.7% less likely to have a stroke based on both the total PA (odds ratio [OR] 0.643, 95% confidence interval [CI] 0.523-0.790) and LTPA (OR 0.643, 95% CI 0.514-0.805), while OPA or TPA did not demonstrate lower stroke risk. Furthermore, participants with less than 7.5 h/day SA levels were 21.6% (OR 0.784, 95% CI 0.665-0.925) less likely to have a stroke. The intensities of total PA and LTPA exhibited nonlinear U-shaped associations with stroke risk. In contrast, those of OPA and TPA showed negative linear associations, while SA intensities were positively linearly correlated with stroke risk. Conclusions LTPA, but not OPA or TPA, was associated with a lower risk of stroke at any amount, suggesting that significant cardiovascular health would benefit from increased PA. Additionally, the positive association between SA and stroke indicated that prolonged sitting was detrimental to cardiovascular health. Overall, increased PA within a reasonable range reduces the risk of stroke, while increased SA elevates it.
title The association of domain-specific physical activity and sedentary activity with stroke: A prospective cohort study
topic Medical Physics
Quantitative Methods
url https://arxiv.org/abs/2406.13284