Cryogenic cesium iodide as a potential PET material

Fuente: arXiv
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Main Authors: Soleti, S. R., Castillo, A., Collar, J. I., del Barrio-Torregrosa, M., Echeverria, C., Seemann, M., Zerzion, D., Cadenas, J. J. Gómez
Format: Preprint
Published: 2024
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author Soleti, S. R.
Castillo, A.
Collar, J. I.
del Barrio-Torregrosa, M.
Echeverria, C.
Seemann, M.
Zerzion, D.
Cadenas, J. J. Gómez
author_facet Soleti, S. R.
Castillo, A.
Collar, J. I.
del Barrio-Torregrosa, M.
Echeverria, C.
Seemann, M.
Zerzion, D.
Cadenas, J. J. Gómez
contents Total Body PET (TBPET) scanners have recently demonstrated the ability to significantly reduce both acquisition time and the administered radioactive dose, thanks to their increased sensitivity. However, their widespread adoption is limited by the high costs associated with the current available systems. Cesium iodide (CsI), though historically less favored for PET due to its lower stopping power and light yield compared to crystals like LYSO, shows remarkable improvement when operated at cryogenic temperatures ($\sim$100 K). Under these conditions, CsI light yield rises dramatically to about 100 photons/keV, providing excellent energy resolution and good coincidence time resolution at a lower cost - typically 3 to 5 times cheaper than other crystals at parity of radiation length. In our study, we measured the light yield, the energy resolution and the coincidence time resolution as a function of temperature for two pure CsI crystals read out by a pair of silicon photomultipliers (SiPMs). An energy resolution of 6.3% FWHM and a coincidence time resolution of 1.84 ns at 511 keV were achieved at a temperature of 104 K. These results point towards the potential of cryogenic CsI as a cost-effective, high-performance material for TBPET scanners.
format Preprint
id arxiv_https___arxiv_org_abs_2406_13598
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Cryogenic cesium iodide as a potential PET material
Soleti, S. R.
Castillo, A.
Collar, J. I.
del Barrio-Torregrosa, M.
Echeverria, C.
Seemann, M.
Zerzion, D.
Cadenas, J. J. Gómez
Instrumentation and Detectors
Medical Physics
Total Body PET (TBPET) scanners have recently demonstrated the ability to significantly reduce both acquisition time and the administered radioactive dose, thanks to their increased sensitivity. However, their widespread adoption is limited by the high costs associated with the current available systems. Cesium iodide (CsI), though historically less favored for PET due to its lower stopping power and light yield compared to crystals like LYSO, shows remarkable improvement when operated at cryogenic temperatures ($\sim$100 K). Under these conditions, CsI light yield rises dramatically to about 100 photons/keV, providing excellent energy resolution and good coincidence time resolution at a lower cost - typically 3 to 5 times cheaper than other crystals at parity of radiation length. In our study, we measured the light yield, the energy resolution and the coincidence time resolution as a function of temperature for two pure CsI crystals read out by a pair of silicon photomultipliers (SiPMs). An energy resolution of 6.3% FWHM and a coincidence time resolution of 1.84 ns at 511 keV were achieved at a temperature of 104 K. These results point towards the potential of cryogenic CsI as a cost-effective, high-performance material for TBPET scanners.
title Cryogenic cesium iodide as a potential PET material
topic Instrumentation and Detectors
Medical Physics
url https://arxiv.org/abs/2406.13598