Extended error threshold mechanism in {\it quasispecies} theory via population dynamics

Fuente: arXiv
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Hauptverfasser: Velten, Hermano, Pinheiro, Carlos Felipe, Silva, Alcides Castro e
Format: Preprint
Veröffentlicht: 2024
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author Velten, Hermano
Pinheiro, Carlos Felipe
Silva, Alcides Castro e
author_facet Velten, Hermano
Pinheiro, Carlos Felipe
Silva, Alcides Castro e
contents We investigate Eigen's model for the evolution of the genetic code of microorganisms using a novel method based on population dynamics analysis. This model, for a given number of offspring, determines long-term survival as a function of the "genetic" information length and copy error probability. There exists a maximum threshold for the quantity of information that can be consistently preserved through the process of evolution within a population of perfectly replicating sequences, meaning no errors are allowed. With our formula, we expand upon the traditional error threshold formula of Eigen's theory and introduce a new expression for general cases where the self-reproduction process allows up to any integer number of copying errors per digit per replication step.
format Preprint
id arxiv_https___arxiv_org_abs_2406_14516
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Extended error threshold mechanism in {\it quasispecies} theory via population dynamics
Velten, Hermano
Pinheiro, Carlos Felipe
Silva, Alcides Castro e
Populations and Evolution
We investigate Eigen's model for the evolution of the genetic code of microorganisms using a novel method based on population dynamics analysis. This model, for a given number of offspring, determines long-term survival as a function of the "genetic" information length and copy error probability. There exists a maximum threshold for the quantity of information that can be consistently preserved through the process of evolution within a population of perfectly replicating sequences, meaning no errors are allowed. With our formula, we expand upon the traditional error threshold formula of Eigen's theory and introduce a new expression for general cases where the self-reproduction process allows up to any integer number of copying errors per digit per replication step.
title Extended error threshold mechanism in {\it quasispecies} theory via population dynamics
topic Populations and Evolution
url https://arxiv.org/abs/2406.14516