On Instabilities of Unsupervised Denoising Diffusion Models in Magnetic Resonance Imaging Reconstruction

Fuente: arXiv
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Autori principali: Han, Tianyu, Nebelung, Sven, Khader, Firas, Kather, Jakob Nikolas, Truhn, Daniel
Natura: Preprint
Pubblicazione: 2024
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author Han, Tianyu
Nebelung, Sven
Khader, Firas
Kather, Jakob Nikolas
Truhn, Daniel
author_facet Han, Tianyu
Nebelung, Sven
Khader, Firas
Kather, Jakob Nikolas
Truhn, Daniel
contents Denoising diffusion models offer a promising approach to accelerating magnetic resonance imaging (MRI) and producing diagnostic-level images in an unsupervised manner. However, our study demonstrates that even tiny worst-case potential perturbations transferred from a surrogate model can cause these models to generate fake tissue structures that may mislead clinicians. The transferability of such worst-case perturbations indicates that the robustness of image reconstruction may be compromised due to MR system imperfections or other sources of noise. Moreover, at larger perturbation strengths, diffusion models exhibit Gaussian noise-like artifacts that are distinct from those observed in supervised models and are more challenging to detect. Our results highlight the vulnerability of current state-of-the-art diffusion-based reconstruction models to possible worst-case perturbations and underscore the need for further research to improve their robustness and reliability in clinical settings.
format Preprint
id arxiv_https___arxiv_org_abs_2406_16983
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle On Instabilities of Unsupervised Denoising Diffusion Models in Magnetic Resonance Imaging Reconstruction
Han, Tianyu
Nebelung, Sven
Khader, Firas
Kather, Jakob Nikolas
Truhn, Daniel
Image and Video Processing
Artificial Intelligence
Machine Learning
Denoising diffusion models offer a promising approach to accelerating magnetic resonance imaging (MRI) and producing diagnostic-level images in an unsupervised manner. However, our study demonstrates that even tiny worst-case potential perturbations transferred from a surrogate model can cause these models to generate fake tissue structures that may mislead clinicians. The transferability of such worst-case perturbations indicates that the robustness of image reconstruction may be compromised due to MR system imperfections or other sources of noise. Moreover, at larger perturbation strengths, diffusion models exhibit Gaussian noise-like artifacts that are distinct from those observed in supervised models and are more challenging to detect. Our results highlight the vulnerability of current state-of-the-art diffusion-based reconstruction models to possible worst-case perturbations and underscore the need for further research to improve their robustness and reliability in clinical settings.
title On Instabilities of Unsupervised Denoising Diffusion Models in Magnetic Resonance Imaging Reconstruction
topic Image and Video Processing
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2406.16983