Large Language Models for Cuffless Blood Pressure Measurement From Wearable Biosignals

Fuente: arXiv
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Main Authors: Liu, Zengding, Chen, Chen, Cao, Jiannong, Pan, Minglei, Liu, Jikui, Li, Nan, Miao, Fen, Li, Ye
Format: Preprint
Published: 2024
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_version_ 1866911945301426176
author Liu, Zengding
Chen, Chen
Cao, Jiannong
Pan, Minglei
Liu, Jikui
Li, Nan
Miao, Fen
Li, Ye
author_facet Liu, Zengding
Chen, Chen
Cao, Jiannong
Pan, Minglei
Liu, Jikui
Li, Nan
Miao, Fen
Li, Ye
contents Large language models (LLMs) have captured significant interest from both academia and industry due to their impressive performance across various textual tasks. However, the potential of LLMs to analyze physiological time-series data remains an emerging research field. Particularly, there is a notable gap in the utilization of LLMs for analyzing wearable biosignals to achieve cuffless blood pressure (BP) measurement, which is critical for the management of cardiovascular diseases. This paper presents the first work to explore the capacity of LLMs to perform cuffless BP estimation based on wearable biosignals. We extracted physiological features from electrocardiogram (ECG) and photoplethysmogram (PPG) signals and designed context-enhanced prompts by combining these features with BP domain knowledge and user information. Subsequently, we adapted LLMs to BP estimation tasks through fine-tuning. To evaluate the proposed approach, we conducted assessments of ten advanced LLMs using a comprehensive public dataset of wearable biosignals from 1,272 participants. The experimental results demonstrate that the optimally fine-tuned LLM significantly surpasses conventional task-specific baselines, achieving an estimation error of 0.00 $\pm$ 9.25 mmHg for systolic BP and 1.29 $\pm$ 6.37 mmHg for diastolic BP. Notably, the ablation studies highlight the benefits of our context enhancement strategy, leading to an 8.9% reduction in mean absolute error for systolic BP estimation. This paper pioneers the exploration of LLMs for cuffless BP measurement, providing a potential solution to enhance the accuracy of cuffless BP measurement.
format Preprint
id arxiv_https___arxiv_org_abs_2406_18069
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Large Language Models for Cuffless Blood Pressure Measurement From Wearable Biosignals
Liu, Zengding
Chen, Chen
Cao, Jiannong
Pan, Minglei
Liu, Jikui
Li, Nan
Miao, Fen
Li, Ye
Signal Processing
Artificial Intelligence
Computation and Language
Large language models (LLMs) have captured significant interest from both academia and industry due to their impressive performance across various textual tasks. However, the potential of LLMs to analyze physiological time-series data remains an emerging research field. Particularly, there is a notable gap in the utilization of LLMs for analyzing wearable biosignals to achieve cuffless blood pressure (BP) measurement, which is critical for the management of cardiovascular diseases. This paper presents the first work to explore the capacity of LLMs to perform cuffless BP estimation based on wearable biosignals. We extracted physiological features from electrocardiogram (ECG) and photoplethysmogram (PPG) signals and designed context-enhanced prompts by combining these features with BP domain knowledge and user information. Subsequently, we adapted LLMs to BP estimation tasks through fine-tuning. To evaluate the proposed approach, we conducted assessments of ten advanced LLMs using a comprehensive public dataset of wearable biosignals from 1,272 participants. The experimental results demonstrate that the optimally fine-tuned LLM significantly surpasses conventional task-specific baselines, achieving an estimation error of 0.00 $\pm$ 9.25 mmHg for systolic BP and 1.29 $\pm$ 6.37 mmHg for diastolic BP. Notably, the ablation studies highlight the benefits of our context enhancement strategy, leading to an 8.9% reduction in mean absolute error for systolic BP estimation. This paper pioneers the exploration of LLMs for cuffless BP measurement, providing a potential solution to enhance the accuracy of cuffless BP measurement.
title Large Language Models for Cuffless Blood Pressure Measurement From Wearable Biosignals
topic Signal Processing
Artificial Intelligence
Computation and Language
url https://arxiv.org/abs/2406.18069