Absolute average and median treatment effects as causal estimands on metric spaces

Fuente: arXiv
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Autori principali: Shin, Ha-Young, Kim, Kyusoon, Lee, Kwonsang, Oh, Hee-Seok
Natura: Preprint
Pubblicazione: 2024
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author Shin, Ha-Young
Kim, Kyusoon
Lee, Kwonsang
Oh, Hee-Seok
author_facet Shin, Ha-Young
Kim, Kyusoon
Lee, Kwonsang
Oh, Hee-Seok
contents We define the notions of absolute average and median treatment effects as causal estimands on general metric spaces such as Riemannian manifolds, propose estimators using stratification, and prove several properties, including strong consistency. In the process, we also demonstrate the strong consistency of the weighted sample Fréchet means and geometric medians. Stratification allows these estimators to be utilized beyond the narrow constraints of a completely randomized experiment. After constructing confidence intervals using bootstrapping, we outline how to use the proposed estimates to test Fisher's sharp null hypothesis that the absolute average or median treatment effect is zero. Empirical evidence for the strong consistency of the estimators and the reasonable asymptotic coverage of the confidence intervals is provided through simulations in both randomized experiments and observational study settings. We also apply our methods to real data from an observational study to investigate the causal relationship between Alzheimer's disease and the shape of the corpus callosum, rejecting the aforementioned null hypotheses in cases where conventional Euclidean methods fail to do so. Our proposed methods are more generally applicable than past studies in dealing with general metric spaces.
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id arxiv_https___arxiv_org_abs_2407_03726
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Absolute average and median treatment effects as causal estimands on metric spaces
Shin, Ha-Young
Kim, Kyusoon
Lee, Kwonsang
Oh, Hee-Seok
Methodology
We define the notions of absolute average and median treatment effects as causal estimands on general metric spaces such as Riemannian manifolds, propose estimators using stratification, and prove several properties, including strong consistency. In the process, we also demonstrate the strong consistency of the weighted sample Fréchet means and geometric medians. Stratification allows these estimators to be utilized beyond the narrow constraints of a completely randomized experiment. After constructing confidence intervals using bootstrapping, we outline how to use the proposed estimates to test Fisher's sharp null hypothesis that the absolute average or median treatment effect is zero. Empirical evidence for the strong consistency of the estimators and the reasonable asymptotic coverage of the confidence intervals is provided through simulations in both randomized experiments and observational study settings. We also apply our methods to real data from an observational study to investigate the causal relationship between Alzheimer's disease and the shape of the corpus callosum, rejecting the aforementioned null hypotheses in cases where conventional Euclidean methods fail to do so. Our proposed methods are more generally applicable than past studies in dealing with general metric spaces.
title Absolute average and median treatment effects as causal estimands on metric spaces
topic Methodology
url https://arxiv.org/abs/2407.03726