Reverse Engineering the Fly Brain Using FlyCircuit Database

Fuente: arXiv
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Auteurs principaux: Ching, Yu-Tai, Cho, Chin-Ping, Tang, Fu-Kai, Chang, Yi-Chiun, Cheng, Chang-Chieh, He, Guan-Wei, Chang, Ann-Shyn, Chuang, Chaochun
Format: Preprint
Publié: 2024
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author Ching, Yu-Tai
Cho, Chin-Ping
Tang, Fu-Kai
Chang, Yi-Chiun
Cheng, Chang-Chieh
He, Guan-Wei
Chang, Ann-Shyn
Chuang, Chaochun
author_facet Ching, Yu-Tai
Cho, Chin-Ping
Tang, Fu-Kai
Chang, Yi-Chiun
Cheng, Chang-Chieh
He, Guan-Wei
Chang, Ann-Shyn
Chuang, Chaochun
contents A method to reverse engineering of a fly brain using the {\it FlyCircuit} database is presented. This method was designed based on the assumption that similar neurons could serve identical functions. We thus cluster the neurons based on the similarity between neurons. The procedures are to partition the neurons in the database into groups, and then assemble the groups into potential modules. Some of the modules correspond to known neuropils, including Medulla were obtained. The same clustering algorithm was applied to analyze Medulla's structure. Another possible application of the clustering result is to study the brain-wide neuron connectome by looking at the connectivity between groups of neurons.
format Preprint
id arxiv_https___arxiv_org_abs_2407_04202
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Reverse Engineering the Fly Brain Using FlyCircuit Database
Ching, Yu-Tai
Cho, Chin-Ping
Tang, Fu-Kai
Chang, Yi-Chiun
Cheng, Chang-Chieh
He, Guan-Wei
Chang, Ann-Shyn
Chuang, Chaochun
Neurons and Cognition
A method to reverse engineering of a fly brain using the {\it FlyCircuit} database is presented. This method was designed based on the assumption that similar neurons could serve identical functions. We thus cluster the neurons based on the similarity between neurons. The procedures are to partition the neurons in the database into groups, and then assemble the groups into potential modules. Some of the modules correspond to known neuropils, including Medulla were obtained. The same clustering algorithm was applied to analyze Medulla's structure. Another possible application of the clustering result is to study the brain-wide neuron connectome by looking at the connectivity between groups of neurons.
title Reverse Engineering the Fly Brain Using FlyCircuit Database
topic Neurons and Cognition
url https://arxiv.org/abs/2407.04202