Enhancing Label-efficient Medical Image Segmentation with Text-guided Diffusion Models

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1. Verfasser: Feng, Chun-Mei
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Veröffentlicht: 2024
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author Feng, Chun-Mei
author_facet Feng, Chun-Mei
contents Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image representation for downstream tasks, e.g., segmentation. However, these latent semantic representations rely heavily on labor-intensive pixel-level annotations as supervision, limiting the usability of DPM in medical image segmentation. To address this limitation, we propose an enhanced diffusion segmentation model, called TextDiff, that improves semantic representation through inexpensive medical text annotations, thereby explicitly establishing semantic representation and language correspondence for diffusion models. Concretely, TextDiff extracts intermediate activations of the Markov step of the reverse diffusion process in a pretrained diffusion model on large-scale natural images and learns additional expert knowledge by combining them with complementary and readily available diagnostic text information. TextDiff freezes the dual-branch multi-modal structure and mines the latent alignment of semantic features in diffusion models with diagnostic descriptions by only training the cross-attention mechanism and pixel classifier, making it possible to enhance semantic representation with inexpensive text. Extensive experiments on public QaTa-COVID19 and MoNuSeg datasets show that our TextDiff is significantly superior to the state-of-the-art multi-modal segmentation methods with only a few training samples.
format Preprint
id arxiv_https___arxiv_org_abs_2407_05323
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Enhancing Label-efficient Medical Image Segmentation with Text-guided Diffusion Models
Feng, Chun-Mei
Image and Video Processing
Computer Vision and Pattern Recognition
Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image representation for downstream tasks, e.g., segmentation. However, these latent semantic representations rely heavily on labor-intensive pixel-level annotations as supervision, limiting the usability of DPM in medical image segmentation. To address this limitation, we propose an enhanced diffusion segmentation model, called TextDiff, that improves semantic representation through inexpensive medical text annotations, thereby explicitly establishing semantic representation and language correspondence for diffusion models. Concretely, TextDiff extracts intermediate activations of the Markov step of the reverse diffusion process in a pretrained diffusion model on large-scale natural images and learns additional expert knowledge by combining them with complementary and readily available diagnostic text information. TextDiff freezes the dual-branch multi-modal structure and mines the latent alignment of semantic features in diffusion models with diagnostic descriptions by only training the cross-attention mechanism and pixel classifier, making it possible to enhance semantic representation with inexpensive text. Extensive experiments on public QaTa-COVID19 and MoNuSeg datasets show that our TextDiff is significantly superior to the state-of-the-art multi-modal segmentation methods with only a few training samples.
title Enhancing Label-efficient Medical Image Segmentation with Text-guided Diffusion Models
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2407.05323