Privacy-Preserving Collaborative Genomic Research: A Real-Life Deployment and Vision

Fuente: arXiv
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Autores principales: Rahmani, Zahra, Shahini, Nahal, Gat, Nadav, Yun, Zebin, Jiang, Yuzhou, Farchy, Ofir, Harel, Yaniv, Chaudhary, Vipin, Sharif, Mahmood, Ayday, Erman
Formato: Preprint
Publicado: 2024
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author Rahmani, Zahra
Shahini, Nahal
Gat, Nadav
Yun, Zebin
Jiang, Yuzhou
Farchy, Ofir
Harel, Yaniv
Chaudhary, Vipin
Sharif, Mahmood
Ayday, Erman
author_facet Rahmani, Zahra
Shahini, Nahal
Gat, Nadav
Yun, Zebin
Jiang, Yuzhou
Farchy, Ofir
Harel, Yaniv
Chaudhary, Vipin
Sharif, Mahmood
Ayday, Erman
contents The data revolution holds significant promise for the health sector. Vast amounts of data collected from individuals will be transformed into knowledge, AI models, predictive systems, and best practices. One area of health that stands to benefit greatly is the genomic domain. Progress in AI, machine learning, and data science has opened new opportunities for genomic research, promising breakthroughs in personalized medicine. However, increasing awareness of privacy and cybersecurity necessitates robust solutions to protect sensitive data in collaborative research. This paper presents a practical deployment of a privacy-preserving framework for genomic research, developed in collaboration with Lynx$.$MD, a platform for secure health data collaboration. The framework addresses critical cybersecurity and privacy challenges, enabling the privacy-preserving sharing and analysis of genomic data while mitigating risks associated with data breaches. By integrating advanced privacy-preserving algorithms, the solution ensures the protection of individual privacy without compromising data utility. A unique feature of the system is its ability to balance trade-offs between data sharing and privacy, providing stakeholders tools to quantify privacy risks and make informed decisions. Implementing the framework within Lynx$.$MD involves encoding genomic data into binary formats and applying noise through controlled perturbation techniques. This approach preserves essential statistical properties of the data, facilitating effective research and analysis. Moreover, the system incorporates real-time data monitoring and advanced visualization tools, enhancing user experience and decision-making. The paper highlights the need for tailored privacy attacks and defenses specific to genomic data. Addressing these challenges fosters collaboration in genomic research, advancing personalized medicine and public health.
format Preprint
id arxiv_https___arxiv_org_abs_2407_09004
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Privacy-Preserving Collaborative Genomic Research: A Real-Life Deployment and Vision
Rahmani, Zahra
Shahini, Nahal
Gat, Nadav
Yun, Zebin
Jiang, Yuzhou
Farchy, Ofir
Harel, Yaniv
Chaudhary, Vipin
Sharif, Mahmood
Ayday, Erman
Cryptography and Security
The data revolution holds significant promise for the health sector. Vast amounts of data collected from individuals will be transformed into knowledge, AI models, predictive systems, and best practices. One area of health that stands to benefit greatly is the genomic domain. Progress in AI, machine learning, and data science has opened new opportunities for genomic research, promising breakthroughs in personalized medicine. However, increasing awareness of privacy and cybersecurity necessitates robust solutions to protect sensitive data in collaborative research. This paper presents a practical deployment of a privacy-preserving framework for genomic research, developed in collaboration with Lynx$.$MD, a platform for secure health data collaboration. The framework addresses critical cybersecurity and privacy challenges, enabling the privacy-preserving sharing and analysis of genomic data while mitigating risks associated with data breaches. By integrating advanced privacy-preserving algorithms, the solution ensures the protection of individual privacy without compromising data utility. A unique feature of the system is its ability to balance trade-offs between data sharing and privacy, providing stakeholders tools to quantify privacy risks and make informed decisions. Implementing the framework within Lynx$.$MD involves encoding genomic data into binary formats and applying noise through controlled perturbation techniques. This approach preserves essential statistical properties of the data, facilitating effective research and analysis. Moreover, the system incorporates real-time data monitoring and advanced visualization tools, enhancing user experience and decision-making. The paper highlights the need for tailored privacy attacks and defenses specific to genomic data. Addressing these challenges fosters collaboration in genomic research, advancing personalized medicine and public health.
title Privacy-Preserving Collaborative Genomic Research: A Real-Life Deployment and Vision
topic Cryptography and Security
url https://arxiv.org/abs/2407.09004