Deep Learning Algorithms for Early Diagnosis of Acute Lymphoblastic Leukemia

Fuente: arXiv
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Main Authors: Papaioannou, Dimitris, Christou, Ioannis, Anagnou, Nikos, Chatziioannou, Aristotelis
Format: Preprint
Published: 2024
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author Papaioannou, Dimitris
Christou, Ioannis
Anagnou, Nikos
Chatziioannou, Aristotelis
author_facet Papaioannou, Dimitris
Christou, Ioannis
Anagnou, Nikos
Chatziioannou, Aristotelis
contents Acute lymphoblastic leukemia (ALL) is a form of blood cancer that affects the white blood cells. ALL constitutes approximately 25% of pediatric cancers. Early diagnosis and treatment of ALL are crucial for improving patient outcomes. The task of identifying immature leukemic blasts from normal cells under the microscope can prove challenging, since the images of a healthy and cancerous cell appear similar morphologically. In this study, we propose a binary image classification model to assist in the diagnostic process of ALL. Our model takes as input microscopic images of blood samples and outputs a binary prediction of whether the sample is normal or cancerous. Our dataset consists of 10661 images out of 118 subjects. Deep learning techniques on convolutional neural network architectures were used to achieve accurate classification results. Our proposed method achieved 94.3% accuracy and could be used as an assisting tool for hematologists trying to predict the likelihood of a patient developing ALL.
format Preprint
id arxiv_https___arxiv_org_abs_2407_10251
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Deep Learning Algorithms for Early Diagnosis of Acute Lymphoblastic Leukemia
Papaioannou, Dimitris
Christou, Ioannis
Anagnou, Nikos
Chatziioannou, Aristotelis
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
I.2.6; I.5.4
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that affects the white blood cells. ALL constitutes approximately 25% of pediatric cancers. Early diagnosis and treatment of ALL are crucial for improving patient outcomes. The task of identifying immature leukemic blasts from normal cells under the microscope can prove challenging, since the images of a healthy and cancerous cell appear similar morphologically. In this study, we propose a binary image classification model to assist in the diagnostic process of ALL. Our model takes as input microscopic images of blood samples and outputs a binary prediction of whether the sample is normal or cancerous. Our dataset consists of 10661 images out of 118 subjects. Deep learning techniques on convolutional neural network architectures were used to achieve accurate classification results. Our proposed method achieved 94.3% accuracy and could be used as an assisting tool for hematologists trying to predict the likelihood of a patient developing ALL.
title Deep Learning Algorithms for Early Diagnosis of Acute Lymphoblastic Leukemia
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
I.2.6; I.5.4
url https://arxiv.org/abs/2407.10251