Invariants for level-1 phylogenetic networks under the random walk 4-state Markov model

Fuente: arXiv
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Autori principali: Frohn, M., Holtgrefe, N., van Iersel, L., Jones, M., Kelk, S.
Natura: Preprint
Pubblicazione: 2024
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author Frohn, M.
Holtgrefe, N.
van Iersel, L.
Jones, M.
Kelk, S.
author_facet Frohn, M.
Holtgrefe, N.
van Iersel, L.
Jones, M.
Kelk, S.
contents Phylogenetic networks can represent evolutionary events that cannot be described by phylogenetic trees, such as hybridization, introgression, and lateral gene transfer. Studying phylogenetic networks under a statistical model of DNA sequence evolution can aid the inference of phylogenetic networks. Most notably Markov models like the Jukes-Cantor or Kimura-3 model can been employed to infer a phylogenetic network using phylogenetic invariants. In this article we determine all quadratic invariants for sunlet networks under the random walk 4-state Markov model, which includes the aforementioned models. Taking toric fiber products of trees and sunlet networks, we obtain a new class of invariants for level-1 phylogenetic networks under the same model. Furthermore, we apply our results to the identifiability problem of a network parameter. In particular, we prove that our new class of invariants of the studied model is not sufficient to derive identifiability of quarnets (4-leaf networks). Moreover, we provide an efficient method that is faster and more reliable than the state-of-the-art in finding a significant number of invariants for many level-1 phylogenetic networks.
format Preprint
id arxiv_https___arxiv_org_abs_2407_11720
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Invariants for level-1 phylogenetic networks under the random walk 4-state Markov model
Frohn, M.
Holtgrefe, N.
van Iersel, L.
Jones, M.
Kelk, S.
Populations and Evolution
Algebraic Geometry
Phylogenetic networks can represent evolutionary events that cannot be described by phylogenetic trees, such as hybridization, introgression, and lateral gene transfer. Studying phylogenetic networks under a statistical model of DNA sequence evolution can aid the inference of phylogenetic networks. Most notably Markov models like the Jukes-Cantor or Kimura-3 model can been employed to infer a phylogenetic network using phylogenetic invariants. In this article we determine all quadratic invariants for sunlet networks under the random walk 4-state Markov model, which includes the aforementioned models. Taking toric fiber products of trees and sunlet networks, we obtain a new class of invariants for level-1 phylogenetic networks under the same model. Furthermore, we apply our results to the identifiability problem of a network parameter. In particular, we prove that our new class of invariants of the studied model is not sufficient to derive identifiability of quarnets (4-leaf networks). Moreover, we provide an efficient method that is faster and more reliable than the state-of-the-art in finding a significant number of invariants for many level-1 phylogenetic networks.
title Invariants for level-1 phylogenetic networks under the random walk 4-state Markov model
topic Populations and Evolution
Algebraic Geometry
url https://arxiv.org/abs/2407.11720