MedEdit: Counterfactual Diffusion-based Image Editing on Brain MRI

Fuente: arXiv
Saved in:
Bibliographic Details
Main Authors: Alaya, Malek Ben, Lang, Daniel M., Wiestler, Benedikt, Schnabel, Julia A., Bercea, Cosmin I.
Format: Preprint
Published: 2024
Subjects:
Online Access:
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1866929429658206208
author Alaya, Malek Ben
Lang, Daniel M.
Wiestler, Benedikt
Schnabel, Julia A.
Bercea, Cosmin I.
author_facet Alaya, Malek Ben
Lang, Daniel M.
Wiestler, Benedikt
Schnabel, Julia A.
Bercea, Cosmin I.
contents Denoising diffusion probabilistic models enable high-fidelity image synthesis and editing. In biomedicine, these models facilitate counterfactual image editing, producing pairs of images where one is edited to simulate hypothetical conditions. For example, they can model the progression of specific diseases, such as stroke lesions. However, current image editing techniques often fail to generate realistic biomedical counterfactuals, either by inadequately modeling indirect pathological effects like brain atrophy or by excessively altering the scan, which disrupts correspondence to the original images. Here, we propose MedEdit, a conditional diffusion model for medical image editing. MedEdit induces pathology in specific areas while balancing the modeling of disease effects and preserving the integrity of the original scan. We evaluated MedEdit on the Atlas v2.0 stroke dataset using Frechet Inception Distance and Dice scores, outperforming state-of-the-art diffusion-based methods such as Palette (by 45%) and SDEdit (by 61%). Additionally, clinical evaluations by a board-certified neuroradiologist confirmed that MedEdit generated realistic stroke scans indistinguishable from real ones. We believe this work will enable counterfactual image editing research to further advance the development of realistic and clinically useful imaging tools.
format Preprint
id arxiv_https___arxiv_org_abs_2407_15270
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle MedEdit: Counterfactual Diffusion-based Image Editing on Brain MRI
Alaya, Malek Ben
Lang, Daniel M.
Wiestler, Benedikt
Schnabel, Julia A.
Bercea, Cosmin I.
Image and Video Processing
Computer Vision and Pattern Recognition
Denoising diffusion probabilistic models enable high-fidelity image synthesis and editing. In biomedicine, these models facilitate counterfactual image editing, producing pairs of images where one is edited to simulate hypothetical conditions. For example, they can model the progression of specific diseases, such as stroke lesions. However, current image editing techniques often fail to generate realistic biomedical counterfactuals, either by inadequately modeling indirect pathological effects like brain atrophy or by excessively altering the scan, which disrupts correspondence to the original images. Here, we propose MedEdit, a conditional diffusion model for medical image editing. MedEdit induces pathology in specific areas while balancing the modeling of disease effects and preserving the integrity of the original scan. We evaluated MedEdit on the Atlas v2.0 stroke dataset using Frechet Inception Distance and Dice scores, outperforming state-of-the-art diffusion-based methods such as Palette (by 45%) and SDEdit (by 61%). Additionally, clinical evaluations by a board-certified neuroradiologist confirmed that MedEdit generated realistic stroke scans indistinguishable from real ones. We believe this work will enable counterfactual image editing research to further advance the development of realistic and clinically useful imaging tools.
title MedEdit: Counterfactual Diffusion-based Image Editing on Brain MRI
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2407.15270