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Main Authors: Wang, Shishuai, Ma, Hua, Hernandez-Tamames, Juan A., Klein, Stefan, Poot, Dirk H. J.
Format: Preprint
Published: 2024
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Online Access:https://arxiv.org/abs/2407.16477
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author Wang, Shishuai
Ma, Hua
Hernandez-Tamames, Juan A.
Klein, Stefan
Poot, Dirk H. J.
author_facet Wang, Shishuai
Ma, Hua
Hernandez-Tamames, Juan A.
Klein, Stefan
Poot, Dirk H. J.
contents Quantitative MRI (qMRI) offers significant advantages over weighted images by providing objective parameters related to tissue properties. Deep learning-based methods have demonstrated effectiveness in estimating quantitative maps from series of weighted images. In this study, we present qMRI Diffuser, a novel approach to qMRI utilising deep generative models. Specifically, we implemented denoising diffusion probabilistic models (DDPM) for T1 quantification in the brain, framing the estimation of quantitative maps as a conditional generation task. The proposed method is compared with the residual neural network (ResNet) and the recurrent inference machine (RIM) on both phantom and in vivo data. The results indicate that our method achieves improved accuracy and precision in parameter estimation, along with superior visual performance. Moreover, our method inherently incorporates stochasticity, enabling straightforward quantification of uncertainty. Hence, the proposed method holds significant promise for quantitative MR mapping.
format Preprint
id arxiv_https___arxiv_org_abs_2407_16477
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle qMRI Diffuser: Quantitative T1 Mapping of the Brain using a Denoising Diffusion Probabilistic Model
Wang, Shishuai
Ma, Hua
Hernandez-Tamames, Juan A.
Klein, Stefan
Poot, Dirk H. J.
Computer Vision and Pattern Recognition
Quantitative MRI (qMRI) offers significant advantages over weighted images by providing objective parameters related to tissue properties. Deep learning-based methods have demonstrated effectiveness in estimating quantitative maps from series of weighted images. In this study, we present qMRI Diffuser, a novel approach to qMRI utilising deep generative models. Specifically, we implemented denoising diffusion probabilistic models (DDPM) for T1 quantification in the brain, framing the estimation of quantitative maps as a conditional generation task. The proposed method is compared with the residual neural network (ResNet) and the recurrent inference machine (RIM) on both phantom and in vivo data. The results indicate that our method achieves improved accuracy and precision in parameter estimation, along with superior visual performance. Moreover, our method inherently incorporates stochasticity, enabling straightforward quantification of uncertainty. Hence, the proposed method holds significant promise for quantitative MR mapping.
title qMRI Diffuser: Quantitative T1 Mapping of the Brain using a Denoising Diffusion Probabilistic Model
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2407.16477