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Main Authors: Kim, Inkoo, Jeong, Daun, Weisburn, Leah, Alexiu, Alexandra, Van Voorhis, Troy, Rhee, Young Min, Son, Won-Joon, Kim, Hyung-Jin, Yim, Jinkyu, Kim, Sungmin, Cho, Yeonchoo, Jang, Inkook, Lee, Seungmin, Kim, Dae Sin
Format: Preprint
Published: 2024
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Online Access:https://arxiv.org/abs/2407.16586
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author Kim, Inkoo
Jeong, Daun
Weisburn, Leah
Alexiu, Alexandra
Van Voorhis, Troy
Rhee, Young Min
Son, Won-Joon
Kim, Hyung-Jin
Yim, Jinkyu
Kim, Sungmin
Cho, Yeonchoo
Jang, Inkook
Lee, Seungmin
Kim, Dae Sin
author_facet Kim, Inkoo
Jeong, Daun
Weisburn, Leah
Alexiu, Alexandra
Van Voorhis, Troy
Rhee, Young Min
Son, Won-Joon
Kim, Hyung-Jin
Yim, Jinkyu
Kim, Sungmin
Cho, Yeonchoo
Jang, Inkook
Lee, Seungmin
Kim, Dae Sin
contents Modern graphics processing units (GPUs) provide an unprecedented level of computing power. In this study, we present a high-performance, multi-GPU implementation of the analytical nuclear gradient for Kohn-Sham time-dependent density functional theory (TDDFT), employing the Tamm-Dancoff approximation (TDA) and Gaussian-type atomic orbitals as basis functions. We discuss GPU-efficient algorithms for the derivatives of electron repulsion integrals and exchange-correlation functionals within the range-separated scheme. As an illustrative example, we calculated the TDA-TDDFT gradient of the S1 state of a full-scale green fluorescent protein with explicit water solvent molecules, totaling 4353 atoms, at the wB97X/def2-SVP level of theory. Our algorithm demonstrates favorable parallel efficiencies on a high-speed distributed system equipped with 256 Nvidia A100 GPUs, achieving >70% with up to 64 GPUs and 31% with 256 GPUs, effectively leveraging the capabilities of modern high-performance computing systems.
format Preprint
id arxiv_https___arxiv_org_abs_2407_16586
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Very-Large-Scale GPU-Accelerated Nuclear Gradient of Time-Dependent Density Functional Theory with Tamm-Dancoff Approximation and Range-Separated Hybrid Functionals
Kim, Inkoo
Jeong, Daun
Weisburn, Leah
Alexiu, Alexandra
Van Voorhis, Troy
Rhee, Young Min
Son, Won-Joon
Kim, Hyung-Jin
Yim, Jinkyu
Kim, Sungmin
Cho, Yeonchoo
Jang, Inkook
Lee, Seungmin
Kim, Dae Sin
Chemical Physics
Modern graphics processing units (GPUs) provide an unprecedented level of computing power. In this study, we present a high-performance, multi-GPU implementation of the analytical nuclear gradient for Kohn-Sham time-dependent density functional theory (TDDFT), employing the Tamm-Dancoff approximation (TDA) and Gaussian-type atomic orbitals as basis functions. We discuss GPU-efficient algorithms for the derivatives of electron repulsion integrals and exchange-correlation functionals within the range-separated scheme. As an illustrative example, we calculated the TDA-TDDFT gradient of the S1 state of a full-scale green fluorescent protein with explicit water solvent molecules, totaling 4353 atoms, at the wB97X/def2-SVP level of theory. Our algorithm demonstrates favorable parallel efficiencies on a high-speed distributed system equipped with 256 Nvidia A100 GPUs, achieving >70% with up to 64 GPUs and 31% with 256 GPUs, effectively leveraging the capabilities of modern high-performance computing systems.
title Very-Large-Scale GPU-Accelerated Nuclear Gradient of Time-Dependent Density Functional Theory with Tamm-Dancoff Approximation and Range-Separated Hybrid Functionals
topic Chemical Physics
url https://arxiv.org/abs/2407.16586