CardioLab: Laboratory Values Estimation from Electrocardiogram Features - An Exploratory Study

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Autori principali: Alcaraz, Juan Miguel Lopez, Strodthoff, Nils
Natura: Preprint
Pubblicazione: 2024
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author Alcaraz, Juan Miguel Lopez
Strodthoff, Nils
author_facet Alcaraz, Juan Miguel Lopez
Strodthoff, Nils
contents Laboratory value represents a cornerstone of medical diagnostics, but suffers from slow turnaround times, and high costs and only provides information about a single point in time. The continuous estimation of laboratory values from non-invasive data such as electrocardiogram (ECG) would therefore mark a significant frontier in healthcare monitoring. Despite its potential, this domain remains relatively underexplored. In this preliminary study, we used a publicly available dataset (MIMIC-IV-ECG) to investigate the feasibility of inferring laboratory values from ECG features and patient demographics using tree-based models (XGBoost). We define the prediction task as a binary problem of whether the lab value falls into low or high abnormalities. We assessed model performance with AUROC. Our findings demonstrate promising results in the estimation of laboratory values related to different organ systems. While further research and validation are warranted to fully assess the clinical utility and generalizability of the approach, our findings lay the groundwork for future investigations for laboratory value estimation using ECG data. Such advancements hold promise for revolutionizing predictive healthcare applications, offering faster, non-invasive, and more affordable means of patient monitoring.
format Preprint
id arxiv_https___arxiv_org_abs_2407_18629
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle CardioLab: Laboratory Values Estimation from Electrocardiogram Features - An Exploratory Study
Alcaraz, Juan Miguel Lopez
Strodthoff, Nils
Signal Processing
Machine Learning
Applications
Laboratory value represents a cornerstone of medical diagnostics, but suffers from slow turnaround times, and high costs and only provides information about a single point in time. The continuous estimation of laboratory values from non-invasive data such as electrocardiogram (ECG) would therefore mark a significant frontier in healthcare monitoring. Despite its potential, this domain remains relatively underexplored. In this preliminary study, we used a publicly available dataset (MIMIC-IV-ECG) to investigate the feasibility of inferring laboratory values from ECG features and patient demographics using tree-based models (XGBoost). We define the prediction task as a binary problem of whether the lab value falls into low or high abnormalities. We assessed model performance with AUROC. Our findings demonstrate promising results in the estimation of laboratory values related to different organ systems. While further research and validation are warranted to fully assess the clinical utility and generalizability of the approach, our findings lay the groundwork for future investigations for laboratory value estimation using ECG data. Such advancements hold promise for revolutionizing predictive healthcare applications, offering faster, non-invasive, and more affordable means of patient monitoring.
title CardioLab: Laboratory Values Estimation from Electrocardiogram Features - An Exploratory Study
topic Signal Processing
Machine Learning
Applications
url https://arxiv.org/abs/2407.18629