Knowledge-Guided Prompt Learning for Lifespan Brain MR Image Segmentation

Fuente: arXiv
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Main Authors: Teng, Lin, Zhao, Zihao, Huang, Jiawei, Cao, Zehong, Meng, Runqi, Shi, Feng, Shen, Dinggang
Format: Preprint
Published: 2024
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author Teng, Lin
Zhao, Zihao
Huang, Jiawei
Cao, Zehong
Meng, Runqi
Shi, Feng
Shen, Dinggang
author_facet Teng, Lin
Zhao, Zihao
Huang, Jiawei
Cao, Zehong
Meng, Runqi
Shi, Feng
Shen, Dinggang
contents Automatic and accurate segmentation of brain MR images throughout the human lifespan into tissue and structure is crucial for understanding brain development and diagnosing diseases. However, challenges arise from the intricate variations in brain appearance due to rapid early brain development, aging, and disorders, compounded by the limited availability of manually-labeled datasets. In response, we present a two-step segmentation framework employing Knowledge-Guided Prompt Learning (KGPL) for brain MRI. Specifically, we first pre-train segmentation models on large-scale datasets with sub-optimal labels, followed by the incorporation of knowledge-driven embeddings learned from image-text alignment into the models. The introduction of knowledge-wise prompts captures semantic relationships between anatomical variability and biological processes, enabling models to learn structural feature embeddings across diverse age groups. Experimental findings demonstrate the superiority and robustness of our proposed method, particularly noticeable when employing Swin UNETR as the backbone. Our approach achieves average DSC values of 95.17% and 94.19% for brain tissue and structure segmentation, respectively. Our code is available at https://github.com/TL9792/KGPL.
format Preprint
id arxiv_https___arxiv_org_abs_2407_21328
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Knowledge-Guided Prompt Learning for Lifespan Brain MR Image Segmentation
Teng, Lin
Zhao, Zihao
Huang, Jiawei
Cao, Zehong
Meng, Runqi
Shi, Feng
Shen, Dinggang
Image and Video Processing
Computer Vision and Pattern Recognition
Automatic and accurate segmentation of brain MR images throughout the human lifespan into tissue and structure is crucial for understanding brain development and diagnosing diseases. However, challenges arise from the intricate variations in brain appearance due to rapid early brain development, aging, and disorders, compounded by the limited availability of manually-labeled datasets. In response, we present a two-step segmentation framework employing Knowledge-Guided Prompt Learning (KGPL) for brain MRI. Specifically, we first pre-train segmentation models on large-scale datasets with sub-optimal labels, followed by the incorporation of knowledge-driven embeddings learned from image-text alignment into the models. The introduction of knowledge-wise prompts captures semantic relationships between anatomical variability and biological processes, enabling models to learn structural feature embeddings across diverse age groups. Experimental findings demonstrate the superiority and robustness of our proposed method, particularly noticeable when employing Swin UNETR as the backbone. Our approach achieves average DSC values of 95.17% and 94.19% for brain tissue and structure segmentation, respectively. Our code is available at https://github.com/TL9792/KGPL.
title Knowledge-Guided Prompt Learning for Lifespan Brain MR Image Segmentation
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2407.21328