Accelerating Domain-Aware Electron Microscopy Analysis Using Deep Learning Models with Synthetic Data and Image-Wide Confidence Scoring

Fuente: arXiv
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Main Authors: Lynch, Matthew J., Jacobs, Ryan, Bruno, Gabriella, Patki, Priyam, Morgan, Dane, Field, Kevin G.
Format: Preprint
Published: 2024
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_version_ 1866911135177900032
author Lynch, Matthew J.
Jacobs, Ryan
Bruno, Gabriella
Patki, Priyam
Morgan, Dane
Field, Kevin G.
author_facet Lynch, Matthew J.
Jacobs, Ryan
Bruno, Gabriella
Patki, Priyam
Morgan, Dane
Field, Kevin G.
contents The integration of machine learning (ML) models enhances the efficiency, affordability, and reliability of feature detection in microscopy, yet their development and applicability are hindered by the dependency on scarce and often flawed manually labeled datasets and a lack of domain awareness. We addressed these challenges by creating a physics-based synthetic image and data generator, resulting in a machine learning model that achieves comparable precision (0.86), recall (0.63), F1 scores (0.71), and engineering property predictions (R2=0.82) to a model trained on human-labeled data. We enhanced both models by using feature prediction confidence scores to derive an image-wide confidence metric, enabling simple thresholding to eliminate ambiguous and out-of-domain images resulting in performance boosts of 5-30% with a filtering-out rate of 25%. Our study demonstrates that synthetic data can eliminate human reliance in ML and provides a means for domain awareness in cases where many feature detections per image are needed.
format Preprint
id arxiv_https___arxiv_org_abs_2408_01558
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Accelerating Domain-Aware Electron Microscopy Analysis Using Deep Learning Models with Synthetic Data and Image-Wide Confidence Scoring
Lynch, Matthew J.
Jacobs, Ryan
Bruno, Gabriella
Patki, Priyam
Morgan, Dane
Field, Kevin G.
Computer Vision and Pattern Recognition
Materials Science
The integration of machine learning (ML) models enhances the efficiency, affordability, and reliability of feature detection in microscopy, yet their development and applicability are hindered by the dependency on scarce and often flawed manually labeled datasets and a lack of domain awareness. We addressed these challenges by creating a physics-based synthetic image and data generator, resulting in a machine learning model that achieves comparable precision (0.86), recall (0.63), F1 scores (0.71), and engineering property predictions (R2=0.82) to a model trained on human-labeled data. We enhanced both models by using feature prediction confidence scores to derive an image-wide confidence metric, enabling simple thresholding to eliminate ambiguous and out-of-domain images resulting in performance boosts of 5-30% with a filtering-out rate of 25%. Our study demonstrates that synthetic data can eliminate human reliance in ML and provides a means for domain awareness in cases where many feature detections per image are needed.
title Accelerating Domain-Aware Electron Microscopy Analysis Using Deep Learning Models with Synthetic Data and Image-Wide Confidence Scoring
topic Computer Vision and Pattern Recognition
Materials Science
url https://arxiv.org/abs/2408.01558