MedSyn: LLM-based Synthetic Medical Text Generation Framework

Fuente: arXiv
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Autori principali: Kumichev, Gleb, Blinov, Pavel, Kuzkina, Yulia, Goncharov, Vasily, Zubkova, Galina, Zenovkin, Nikolai, Goncharov, Aleksei, Savchenko, Andrey
Natura: Preprint
Pubblicazione: 2024
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author Kumichev, Gleb
Blinov, Pavel
Kuzkina, Yulia
Goncharov, Vasily
Zubkova, Galina
Zenovkin, Nikolai
Goncharov, Aleksei
Savchenko, Andrey
author_facet Kumichev, Gleb
Blinov, Pavel
Kuzkina, Yulia
Goncharov, Vasily
Zubkova, Galina
Zenovkin, Nikolai
Goncharov, Aleksei
Savchenko, Andrey
contents Generating synthetic text addresses the challenge of data availability in privacy-sensitive domains such as healthcare. This study explores the applicability of synthetic data in real-world medical settings. We introduce MedSyn, a novel medical text generation framework that integrates large language models with a Medical Knowledge Graph (MKG). We use MKG to sample prior medical information for the prompt and generate synthetic clinical notes with GPT-4 and fine-tuned LLaMA models. We assess the benefit of synthetic data through application in the ICD code prediction task. Our research indicates that synthetic data can increase the classification accuracy of vital and challenging codes by up to 17.8% compared to settings without synthetic data. Furthermore, to provide new data for further research in the healthcare domain, we present the largest open-source synthetic dataset of clinical notes for the Russian language, comprising over 41k samples covering 219 ICD-10 codes.
format Preprint
id arxiv_https___arxiv_org_abs_2408_02056
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle MedSyn: LLM-based Synthetic Medical Text Generation Framework
Kumichev, Gleb
Blinov, Pavel
Kuzkina, Yulia
Goncharov, Vasily
Zubkova, Galina
Zenovkin, Nikolai
Goncharov, Aleksei
Savchenko, Andrey
Computation and Language
Machine Learning
Generating synthetic text addresses the challenge of data availability in privacy-sensitive domains such as healthcare. This study explores the applicability of synthetic data in real-world medical settings. We introduce MedSyn, a novel medical text generation framework that integrates large language models with a Medical Knowledge Graph (MKG). We use MKG to sample prior medical information for the prompt and generate synthetic clinical notes with GPT-4 and fine-tuned LLaMA models. We assess the benefit of synthetic data through application in the ICD code prediction task. Our research indicates that synthetic data can increase the classification accuracy of vital and challenging codes by up to 17.8% compared to settings without synthetic data. Furthermore, to provide new data for further research in the healthcare domain, we present the largest open-source synthetic dataset of clinical notes for the Russian language, comprising over 41k samples covering 219 ICD-10 codes.
title MedSyn: LLM-based Synthetic Medical Text Generation Framework
topic Computation and Language
Machine Learning
url https://arxiv.org/abs/2408.02056