Predicting Lung Cancer Patient Prognosis with Large Language Models

Fuente: arXiv
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Autori principali: Hu, Danqing, Liu, Bing, Li, Xiang, Zhu, Xiaofeng, Wu, Nan
Natura: Preprint
Pubblicazione: 2024
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author Hu, Danqing
Liu, Bing
Li, Xiang
Zhu, Xiaofeng
Wu, Nan
author_facet Hu, Danqing
Liu, Bing
Li, Xiang
Zhu, Xiaofeng
Wu, Nan
contents Prognosis prediction is crucial for determining optimal treatment plans for lung cancer patients. Traditionally, such predictions relied on models developed from retrospective patient data. Recently, large language models (LLMs) have gained attention for their ability to process and generate text based on extensive learned knowledge. In this study, we evaluate the potential of GPT-4o mini and GPT-3.5 in predicting the prognosis of lung cancer patients. We collected two prognosis datasets, i.e., survival and post-operative complication datasets, and designed multiple tasks to assess the models' performance comprehensively. Logistic regression models were also developed as baselines for comparison. The experimental results demonstrate that LLMs can achieve competitive, and in some tasks superior, performance in lung cancer prognosis prediction compared to data-driven logistic regression models despite not using additional patient data. These findings suggest that LLMs can be effective tools for prognosis prediction in lung cancer, particularly when patient data is limited or unavailable.
format Preprint
id arxiv_https___arxiv_org_abs_2408_07971
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Predicting Lung Cancer Patient Prognosis with Large Language Models
Hu, Danqing
Liu, Bing
Li, Xiang
Zhu, Xiaofeng
Wu, Nan
Computation and Language
Prognosis prediction is crucial for determining optimal treatment plans for lung cancer patients. Traditionally, such predictions relied on models developed from retrospective patient data. Recently, large language models (LLMs) have gained attention for their ability to process and generate text based on extensive learned knowledge. In this study, we evaluate the potential of GPT-4o mini and GPT-3.5 in predicting the prognosis of lung cancer patients. We collected two prognosis datasets, i.e., survival and post-operative complication datasets, and designed multiple tasks to assess the models' performance comprehensively. Logistic regression models were also developed as baselines for comparison. The experimental results demonstrate that LLMs can achieve competitive, and in some tasks superior, performance in lung cancer prognosis prediction compared to data-driven logistic regression models despite not using additional patient data. These findings suggest that LLMs can be effective tools for prognosis prediction in lung cancer, particularly when patient data is limited or unavailable.
title Predicting Lung Cancer Patient Prognosis with Large Language Models
topic Computation and Language
url https://arxiv.org/abs/2408.07971