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| Main Authors: | , , , |
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| Format: | Preprint |
| Published: |
2024
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| Subjects: | |
| Online Access: | https://arxiv.org/abs/2408.08039 |
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| _version_ | 1866917750233890816 |
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| author | Torres-Cubillo, Antonia Teuber, Andrea Halir, Robert Mizaikoff, Boris |
| author_facet | Torres-Cubillo, Antonia Teuber, Andrea Halir, Robert Mizaikoff, Boris |
| contents | Mid-infrared absorption spectroscopy is a well-established technique for non-destructive quantitative molecular analysis. Waveguide-integrated sensors provide a particularly compact solution operating with reduced sample volumes while exhibiting exquisite molecular selectivity, sensitivity, and ultra-low limits of detection. Recent advances in mid-infrared technologies along with the integration of on-chip sources, detectors and microfluidics, have brought mid-infrared lab-on-chip systems closer to reality. A variety of material platforms has been proposed for the implementation of such systems. However, the lack of a consistent waveguide design approach renders a fair comparison between different alternatives - and a deliberate material selection - challenging, limiting the development of optimized on-chip spectroscopic devices. In the present study, a systematic waveguide design approach has been developed, facilitating evanescent field absorption-based sensing, in particular for aqueous analytes. Our strategy enables a rigorous comparison of several state-of-the-art thin-film waveguides using parametric expressions to predict the achievable limits of detection of the sensing system, while indicating optimum waveguide dimensions and absorption pathlengths, pivotal for the development of next-generation mid-infrared lab-on-chip devices. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2408_08039 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Optimized waveguides for mid-infrared lab-on-chip systems: A rigorous design approach Torres-Cubillo, Antonia Teuber, Andrea Halir, Robert Mizaikoff, Boris Optics Applied Physics Mid-infrared absorption spectroscopy is a well-established technique for non-destructive quantitative molecular analysis. Waveguide-integrated sensors provide a particularly compact solution operating with reduced sample volumes while exhibiting exquisite molecular selectivity, sensitivity, and ultra-low limits of detection. Recent advances in mid-infrared technologies along with the integration of on-chip sources, detectors and microfluidics, have brought mid-infrared lab-on-chip systems closer to reality. A variety of material platforms has been proposed for the implementation of such systems. However, the lack of a consistent waveguide design approach renders a fair comparison between different alternatives - and a deliberate material selection - challenging, limiting the development of optimized on-chip spectroscopic devices. In the present study, a systematic waveguide design approach has been developed, facilitating evanescent field absorption-based sensing, in particular for aqueous analytes. Our strategy enables a rigorous comparison of several state-of-the-art thin-film waveguides using parametric expressions to predict the achievable limits of detection of the sensing system, while indicating optimum waveguide dimensions and absorption pathlengths, pivotal for the development of next-generation mid-infrared lab-on-chip devices. |
| title | Optimized waveguides for mid-infrared lab-on-chip systems: A rigorous design approach |
| topic | Optics Applied Physics |
| url | https://arxiv.org/abs/2408.08039 |