Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Preprint |
| Published: |
2024
|
| Subjects: | |
| Online Access: | https://arxiv.org/abs/2408.09476 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1866909290311188480 |
|---|---|
| author | Wang, Jun Mao, Yu Guan, Nan Xue, Chun Jason |
| author_facet | Wang, Jun Mao, Yu Guan, Nan Xue, Chun Jason |
| contents | Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has emerged as a powerful approach for addressing these challenges, particularly in cancer classification and detection. This survey provides a comprehensive overview of the challenges and methodologies associated with applying MIL to WSI analysis, including attention mechanisms, pseudo-labeling, transformers, pooling functions, and graph neural networks. Additionally, it explores the potential of MIL in discovering cancer cell morphology, constructing interpretable machine learning models, and quantifying cancer grading. By summarizing the current challenges, methodologies, and potential applications of MIL in WSI analysis, this survey aims to inform researchers about the state of the field and inspire future research directions. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2408_09476 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Advances in Multiple Instance Learning for Whole Slide Image Analysis: Techniques, Challenges, and Future Directions Wang, Jun Mao, Yu Guan, Nan Xue, Chun Jason Computer Vision and Pattern Recognition Machine Learning Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has emerged as a powerful approach for addressing these challenges, particularly in cancer classification and detection. This survey provides a comprehensive overview of the challenges and methodologies associated with applying MIL to WSI analysis, including attention mechanisms, pseudo-labeling, transformers, pooling functions, and graph neural networks. Additionally, it explores the potential of MIL in discovering cancer cell morphology, constructing interpretable machine learning models, and quantifying cancer grading. By summarizing the current challenges, methodologies, and potential applications of MIL in WSI analysis, this survey aims to inform researchers about the state of the field and inspire future research directions. |
| title | Advances in Multiple Instance Learning for Whole Slide Image Analysis: Techniques, Challenges, and Future Directions |
| topic | Computer Vision and Pattern Recognition Machine Learning |
| url | https://arxiv.org/abs/2408.09476 |