A two-sample test based on averaged Wilcoxon rank sums over interpoint distances

Fuente: arXiv
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Autori principali: Betken, Annika, Marjanovic, Aljosa, Proksch, Katharina
Natura: Preprint
Pubblicazione: 2024
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author Betken, Annika
Marjanovic, Aljosa
Proksch, Katharina
author_facet Betken, Annika
Marjanovic, Aljosa
Proksch, Katharina
contents An important class of two-sample multivariate homogeneity tests is based on identifying differences between the distributions of interpoint distances. While generating distances from point clouds offers a straightforward and intuitive way for dimensionality reduction, it also introduces dependencies to the resulting distance samples. We propose a simple test based on Wilcoxon's rank sum statistic for which we prove asymptotic normality under the null hypothesis and fixed alternatives under mild conditions on the underlying distributions of the point clouds. Furthermore, we show consistency of the test and derive a variance approximation that allows to construct a computationally feasible, distribution-free test with good finite sample performance. The power and robustness of the test for high-dimensional data and low sample sizes is demonstrated by numerical simulations. Finally, we apply the proposed test to case-control testing on microarray data in genetic studies, which is considered a notorious case for a high number of variables and low sample sizes.
format Preprint
id arxiv_https___arxiv_org_abs_2408_10570
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle A two-sample test based on averaged Wilcoxon rank sums over interpoint distances
Betken, Annika
Marjanovic, Aljosa
Proksch, Katharina
Methodology
An important class of two-sample multivariate homogeneity tests is based on identifying differences between the distributions of interpoint distances. While generating distances from point clouds offers a straightforward and intuitive way for dimensionality reduction, it also introduces dependencies to the resulting distance samples. We propose a simple test based on Wilcoxon's rank sum statistic for which we prove asymptotic normality under the null hypothesis and fixed alternatives under mild conditions on the underlying distributions of the point clouds. Furthermore, we show consistency of the test and derive a variance approximation that allows to construct a computationally feasible, distribution-free test with good finite sample performance. The power and robustness of the test for high-dimensional data and low sample sizes is demonstrated by numerical simulations. Finally, we apply the proposed test to case-control testing on microarray data in genetic studies, which is considered a notorious case for a high number of variables and low sample sizes.
title A two-sample test based on averaged Wilcoxon rank sums over interpoint distances
topic Methodology
url https://arxiv.org/abs/2408.10570