Large Language Models for Multimodal Deformable Image Registration

Fuente: arXiv
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Auteurs principaux: Ma, Mingrui, Wang, Weijie, Ning, Jie, He, Jianfeng, Sebe, Nicu, Lepri, Bruno
Format: Preprint
Publié: 2024
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author Ma, Mingrui
Wang, Weijie
Ning, Jie
He, Jianfeng
Sebe, Nicu
Lepri, Bruno
author_facet Ma, Mingrui
Wang, Weijie
Ning, Jie
He, Jianfeng
Sebe, Nicu
Lepri, Bruno
contents The challenge of Multimodal Deformable Image Registration (MDIR) lies in the conversion and alignment of features between images of different modalities. Generative models (GMs) cannot retain the necessary information enough from the source modality to the target one, while non-GMs struggle to align features across these two modalities. In this paper, we propose a novel coarse-to-fine MDIR framework,LLM-Morph, which is applicable to various pre-trained Large Language Models (LLMs) to solve these concerns by aligning the deep features from different modal medical images. Specifically, we first utilize a CNN encoder to extract deep visual features from cross-modal image pairs, then we use the first adapter to adjust these tokens, and use LoRA in pre-trained LLMs to fine-tune their weights, both aimed at eliminating the domain gap between the pre-trained LLMs and the MDIR task. Third, for the alignment of tokens, we utilize other four adapters to transform the LLM-encoded tokens into multi-scale visual features, generating multi-scale deformation fields and facilitating the coarse-to-fine MDIR task. Extensive experiments in MR-CT Abdomen and SR-Reg Brain datasets demonstrate the effectiveness of our framework and the potential of pre-trained LLMs for MDIR task. Our code is availabel at: https://github.com/ninjannn/LLM-Morph.
format Preprint
id arxiv_https___arxiv_org_abs_2408_10703
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Large Language Models for Multimodal Deformable Image Registration
Ma, Mingrui
Wang, Weijie
Ning, Jie
He, Jianfeng
Sebe, Nicu
Lepri, Bruno
Computer Vision and Pattern Recognition
The challenge of Multimodal Deformable Image Registration (MDIR) lies in the conversion and alignment of features between images of different modalities. Generative models (GMs) cannot retain the necessary information enough from the source modality to the target one, while non-GMs struggle to align features across these two modalities. In this paper, we propose a novel coarse-to-fine MDIR framework,LLM-Morph, which is applicable to various pre-trained Large Language Models (LLMs) to solve these concerns by aligning the deep features from different modal medical images. Specifically, we first utilize a CNN encoder to extract deep visual features from cross-modal image pairs, then we use the first adapter to adjust these tokens, and use LoRA in pre-trained LLMs to fine-tune their weights, both aimed at eliminating the domain gap between the pre-trained LLMs and the MDIR task. Third, for the alignment of tokens, we utilize other four adapters to transform the LLM-encoded tokens into multi-scale visual features, generating multi-scale deformation fields and facilitating the coarse-to-fine MDIR task. Extensive experiments in MR-CT Abdomen and SR-Reg Brain datasets demonstrate the effectiveness of our framework and the potential of pre-trained LLMs for MDIR task. Our code is availabel at: https://github.com/ninjannn/LLM-Morph.
title Large Language Models for Multimodal Deformable Image Registration
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2408.10703