Superimposed Hi-C: A Solution Proposed for Identifying Single Cell's Chromosomal Interactions
Fuente:
arXiv
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Preprint |
| Veröffentlicht: |
2024
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1866929471523651584 |
|---|---|
| author | Zhang, Jia Xiao, Li Qi, Peng Zeng, Yaling Chen, Xumeng Liao, Duan-fang Li, Kai |
| author_facet | Zhang, Jia Xiao, Li Qi, Peng Zeng, Yaling Chen, Xumeng Liao, Duan-fang Li, Kai |
| contents | Hi-C sequencing is widely used for analyzing chromosomal interactions. In this study, we propose "superimposed Hi-C" which features paired EcoP15I sites in a linker to facilitate sticky-end ligation with target DNAs. Superimposed Hi-C overcomes Hi-C's technical limitations, enabling the identification of single cell's chromosomal interactions. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2408_13039 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Superimposed Hi-C: A Solution Proposed for Identifying Single Cell's Chromosomal Interactions Zhang, Jia Xiao, Li Qi, Peng Zeng, Yaling Chen, Xumeng Liao, Duan-fang Li, Kai Genomics Hi-C sequencing is widely used for analyzing chromosomal interactions. In this study, we propose "superimposed Hi-C" which features paired EcoP15I sites in a linker to facilitate sticky-end ligation with target DNAs. Superimposed Hi-C overcomes Hi-C's technical limitations, enabling the identification of single cell's chromosomal interactions. |
| title | Superimposed Hi-C: A Solution Proposed for Identifying Single Cell's Chromosomal Interactions |
| topic | Genomics |
| url | https://arxiv.org/abs/2408.13039 |