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Autores principales: Goldsborough, Thibaut, Philps, Ben, O'Callaghan, Alan, Inglis, Fiona, Leplat, Leo, Filby, Andrew, Bilen, Hakan, Bankhead, Peter
Formato: Preprint
Publicado: 2024
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Acceso en línea:https://arxiv.org/abs/2408.15954
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author Goldsborough, Thibaut
Philps, Ben
O'Callaghan, Alan
Inglis, Fiona
Leplat, Leo
Filby, Andrew
Bilen, Hakan
Bankhead, Peter
author_facet Goldsborough, Thibaut
Philps, Ben
O'Callaghan, Alan
Inglis, Fiona
Leplat, Leo
Filby, Andrew
Bilen, Hakan
Bankhead, Peter
contents Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world datasets. These algorithms must not only achieve state-of-the-art accuracy, but also be optimized for efficiency, portability and user-friendliness. Here, we introduce InstanSeg: a novel embedding-based instance segmentation pipeline designed to identify cells and nuclei in microscopy images. Using six public cell segmentation datasets, we demonstrate that InstanSeg can significantly improve accuracy when compared to the most widely used alternative methods, while reducing the processing time by at least 60%. Furthermore, InstanSeg is designed to be fully serializable as TorchScript and supports GPU acceleration on a range of hardware. We provide an open-source implementation of InstanSeg in Python, in addition to a user-friendly, interactive QuPath extension for inference written in Java. Our code and pre-trained models are available at https://github.com/instanseg/instanseg .
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institution arXiv
publishDate 2024
record_format arxiv
spellingShingle InstanSeg: an embedding-based instance segmentation algorithm optimized for accurate, efficient and portable cell segmentation
Goldsborough, Thibaut
Philps, Ben
O'Callaghan, Alan
Inglis, Fiona
Leplat, Leo
Filby, Andrew
Bilen, Hakan
Bankhead, Peter
Computer Vision and Pattern Recognition
Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world datasets. These algorithms must not only achieve state-of-the-art accuracy, but also be optimized for efficiency, portability and user-friendliness. Here, we introduce InstanSeg: a novel embedding-based instance segmentation pipeline designed to identify cells and nuclei in microscopy images. Using six public cell segmentation datasets, we demonstrate that InstanSeg can significantly improve accuracy when compared to the most widely used alternative methods, while reducing the processing time by at least 60%. Furthermore, InstanSeg is designed to be fully serializable as TorchScript and supports GPU acceleration on a range of hardware. We provide an open-source implementation of InstanSeg in Python, in addition to a user-friendly, interactive QuPath extension for inference written in Java. Our code and pre-trained models are available at https://github.com/instanseg/instanseg .
title InstanSeg: an embedding-based instance segmentation algorithm optimized for accurate, efficient and portable cell segmentation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2408.15954