Q-MRS: A Deep Learning Framework for Quantitative Magnetic Resonance Spectra Analysis

Fuente: arXiv
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Autores principales: Wu, Christopher J., Kegeles, Lawrence S., Guo, Jia
Formato: Preprint
Publicado: 2024
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author Wu, Christopher J.
Kegeles, Lawrence S.
Guo, Jia
author_facet Wu, Christopher J.
Kegeles, Lawrence S.
Guo, Jia
contents Magnetic resonance spectroscopy (MRS) is an established technique for studying tissue metabolism, particularly in central nervous system disorders. While powerful and versatile, MRS is often limited by challenges associated with data quality, processing, and quantification. Existing MRS quantification methods face difficulties in balancing model complexity and reproducibility during spectral modeling, often falling into the trap of either oversimplification or over-parameterization. To address these limitations, this study introduces a deep learning (DL) framework that employs transfer learning, in which the model is pre-trained on simulated datasets before it undergoes fine-tuning on in vivo data. The proposed framework showed promising performance when applied to the Philips dataset from the BIG GABA repository and represents an exciting advancement in MRS data analysis.
format Preprint
id arxiv_https___arxiv_org_abs_2408_15999
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Q-MRS: A Deep Learning Framework for Quantitative Magnetic Resonance Spectra Analysis
Wu, Christopher J.
Kegeles, Lawrence S.
Guo, Jia
Quantitative Methods
Machine Learning
Magnetic resonance spectroscopy (MRS) is an established technique for studying tissue metabolism, particularly in central nervous system disorders. While powerful and versatile, MRS is often limited by challenges associated with data quality, processing, and quantification. Existing MRS quantification methods face difficulties in balancing model complexity and reproducibility during spectral modeling, often falling into the trap of either oversimplification or over-parameterization. To address these limitations, this study introduces a deep learning (DL) framework that employs transfer learning, in which the model is pre-trained on simulated datasets before it undergoes fine-tuning on in vivo data. The proposed framework showed promising performance when applied to the Philips dataset from the BIG GABA repository and represents an exciting advancement in MRS data analysis.
title Q-MRS: A Deep Learning Framework for Quantitative Magnetic Resonance Spectra Analysis
topic Quantitative Methods
Machine Learning
url https://arxiv.org/abs/2408.15999