A Deployed Online Reinforcement Learning Algorithm In An Oral Health Clinical Trial

Fuente: arXiv
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Main Authors: Trella, Anna L., Zhang, Kelly W., Jajal, Hinal, Nahum-Shani, Inbal, Shetty, Vivek, Doshi-Velez, Finale, Murphy, Susan A.
Format: Preprint
Published: 2024
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author Trella, Anna L.
Zhang, Kelly W.
Jajal, Hinal
Nahum-Shani, Inbal
Shetty, Vivek
Doshi-Velez, Finale
Murphy, Susan A.
author_facet Trella, Anna L.
Zhang, Kelly W.
Jajal, Hinal
Nahum-Shani, Inbal
Shetty, Vivek
Doshi-Velez, Finale
Murphy, Susan A.
contents Dental disease is a prevalent chronic condition associated with substantial financial burden, personal suffering, and increased risk of systemic diseases. Despite widespread recommendations for twice-daily tooth brushing, adherence to recommended oral self-care behaviors remains sub-optimal due to factors such as forgetfulness and disengagement. To address this, we developed Oralytics, a mHealth intervention system designed to complement clinician-delivered preventative care for marginalized individuals at risk for dental disease. Oralytics incorporates an online reinforcement learning algorithm to determine optimal times to deliver intervention prompts that encourage oral self-care behaviors. We have deployed Oralytics in a registered clinical trial. The deployment required careful design to manage challenges specific to the clinical trials setting in the U.S. In this paper, we (1) highlight key design decisions of the RL algorithm that address these challenges and (2) conduct a re-sampling analysis to evaluate algorithm design decisions. A second phase (randomized control trial) of Oralytics is planned to start in spring 2025.
format Preprint
id arxiv_https___arxiv_org_abs_2409_02069
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle A Deployed Online Reinforcement Learning Algorithm In An Oral Health Clinical Trial
Trella, Anna L.
Zhang, Kelly W.
Jajal, Hinal
Nahum-Shani, Inbal
Shetty, Vivek
Doshi-Velez, Finale
Murphy, Susan A.
Artificial Intelligence
Human-Computer Interaction
Dental disease is a prevalent chronic condition associated with substantial financial burden, personal suffering, and increased risk of systemic diseases. Despite widespread recommendations for twice-daily tooth brushing, adherence to recommended oral self-care behaviors remains sub-optimal due to factors such as forgetfulness and disengagement. To address this, we developed Oralytics, a mHealth intervention system designed to complement clinician-delivered preventative care for marginalized individuals at risk for dental disease. Oralytics incorporates an online reinforcement learning algorithm to determine optimal times to deliver intervention prompts that encourage oral self-care behaviors. We have deployed Oralytics in a registered clinical trial. The deployment required careful design to manage challenges specific to the clinical trials setting in the U.S. In this paper, we (1) highlight key design decisions of the RL algorithm that address these challenges and (2) conduct a re-sampling analysis to evaluate algorithm design decisions. A second phase (randomized control trial) of Oralytics is planned to start in spring 2025.
title A Deployed Online Reinforcement Learning Algorithm In An Oral Health Clinical Trial
topic Artificial Intelligence
Human-Computer Interaction
url https://arxiv.org/abs/2409.02069