MLOmics: Cancer Multi-Omics Database for Machine Learning

Fuente: arXiv
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Hauptverfasser: Yang, Ziwei, Kotoge, Rikuto, Piao, Xihao, Chen, Zheng, Zhu, Lingwei, Gao, Peng, Matsubara, Yasuko, Sakurai, Yasushi, Sun, Jimeng
Format: Preprint
Veröffentlicht: 2024
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author Yang, Ziwei
Kotoge, Rikuto
Piao, Xihao
Chen, Zheng
Zhu, Lingwei
Gao, Peng
Matsubara, Yasuko
Sakurai, Yasushi
Sun, Jimeng
author_facet Yang, Ziwei
Kotoge, Rikuto
Piao, Xihao
Chen, Zheng
Zhu, Lingwei
Gao, Peng
Matsubara, Yasuko
Sakurai, Yasushi
Sun, Jimeng
contents Framing the investigation of diverse cancers as a machine learning problem has recently shown significant potential in multi-omics analysis and cancer research. Empowering these successful machine learning models are the high-quality training datasets with sufficient data volume and adequate preprocessing. However, while there exist several public data portals, including The Cancer Genome Atlas (TCGA) multi-omics initiative or open-bases such as the LinkedOmics, these databases are not off-the-shelf for existing machine learning models. In this paper, we introduce MLOmics, an open cancer multi-omics database aiming at serving better the development and evaluation of bioinformatics and machine learning models. MLOmics contains 8,314 patient samples covering all 32 cancer types with four omics types, stratified features, and extensive baselines. Complementary support for downstream analysis and bio-knowledge linking are also included to support interdisciplinary analysis.
format Preprint
id arxiv_https___arxiv_org_abs_2409_02143
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle MLOmics: Cancer Multi-Omics Database for Machine Learning
Yang, Ziwei
Kotoge, Rikuto
Piao, Xihao
Chen, Zheng
Zhu, Lingwei
Gao, Peng
Matsubara, Yasuko
Sakurai, Yasushi
Sun, Jimeng
Genomics
Machine Learning
Framing the investigation of diverse cancers as a machine learning problem has recently shown significant potential in multi-omics analysis and cancer research. Empowering these successful machine learning models are the high-quality training datasets with sufficient data volume and adequate preprocessing. However, while there exist several public data portals, including The Cancer Genome Atlas (TCGA) multi-omics initiative or open-bases such as the LinkedOmics, these databases are not off-the-shelf for existing machine learning models. In this paper, we introduce MLOmics, an open cancer multi-omics database aiming at serving better the development and evaluation of bioinformatics and machine learning models. MLOmics contains 8,314 patient samples covering all 32 cancer types with four omics types, stratified features, and extensive baselines. Complementary support for downstream analysis and bio-knowledge linking are also included to support interdisciplinary analysis.
title MLOmics: Cancer Multi-Omics Database for Machine Learning
topic Genomics
Machine Learning
url https://arxiv.org/abs/2409.02143