Understanding eGFR Trajectories and Kidney Function Decline via Large Multimodal Models

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Main Authors: Li, Chih-Yuan, Wu, Jun-Ting, Hsu, Chan, Lin, Ming-Yen, Kang, Yihuang
Format: Preprint
Published: 2024
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author Li, Chih-Yuan
Wu, Jun-Ting
Hsu, Chan
Lin, Ming-Yen
Kang, Yihuang
author_facet Li, Chih-Yuan
Wu, Jun-Ting
Hsu, Chan
Lin, Ming-Yen
Kang, Yihuang
contents The estimated Glomerular Filtration Rate (eGFR) is an essential indicator of kidney function in clinical practice. Although traditional equations and Machine Learning (ML) models using clinical and laboratory data can estimate eGFR, accurately predicting future eGFR levels remains a significant challenge for nephrologists and ML researchers. Recent advances demonstrate that Large Language Models (LLMs) and Large Multimodal Models (LMMs) can serve as robust foundation models for diverse applications. This study investigates the potential of LMMs to predict future eGFR levels with a dataset consisting of laboratory and clinical values from 50 patients. By integrating various prompting techniques and ensembles of LMMs, our findings suggest that these models, when combined with precise prompts and visual representations of eGFR trajectories, offer predictive performance comparable to existing ML models. This research extends the application of foundation models and suggests avenues for future studies to harness these models in addressing complex medical forecasting challenges.
format Preprint
id arxiv_https___arxiv_org_abs_2409_02530
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Understanding eGFR Trajectories and Kidney Function Decline via Large Multimodal Models
Li, Chih-Yuan
Wu, Jun-Ting
Hsu, Chan
Lin, Ming-Yen
Kang, Yihuang
Machine Learning
Artificial Intelligence
The estimated Glomerular Filtration Rate (eGFR) is an essential indicator of kidney function in clinical practice. Although traditional equations and Machine Learning (ML) models using clinical and laboratory data can estimate eGFR, accurately predicting future eGFR levels remains a significant challenge for nephrologists and ML researchers. Recent advances demonstrate that Large Language Models (LLMs) and Large Multimodal Models (LMMs) can serve as robust foundation models for diverse applications. This study investigates the potential of LMMs to predict future eGFR levels with a dataset consisting of laboratory and clinical values from 50 patients. By integrating various prompting techniques and ensembles of LMMs, our findings suggest that these models, when combined with precise prompts and visual representations of eGFR trajectories, offer predictive performance comparable to existing ML models. This research extends the application of foundation models and suggests avenues for future studies to harness these models in addressing complex medical forecasting challenges.
title Understanding eGFR Trajectories and Kidney Function Decline via Large Multimodal Models
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2409.02530