Zero-Shot Whole Slide Image Retrieval in Histopathology Using Embeddings of Foundation Models

Fuente: arXiv
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Main Authors: Alfasly, Saghir, Alabtah, Ghazal, Hemati, Sobhan, Kalari, Krishna Rani, Tizhoosh, H. R.
Format: Preprint
Published: 2024
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author Alfasly, Saghir
Alabtah, Ghazal
Hemati, Sobhan
Kalari, Krishna Rani
Tizhoosh, H. R.
author_facet Alfasly, Saghir
Alabtah, Ghazal
Hemati, Sobhan
Kalari, Krishna Rani
Tizhoosh, H. R.
contents We have tested recently published foundation models for histopathology for image retrieval. We report macro average of F1 score for top-1 retrieval, majority of top-3 retrievals, and majority of top-5 retrievals. We perform zero-shot retrievals, i.e., we do not alter embeddings and we do not train any classifier. As test data, we used diagnostic slides of TCGA, The Cancer Genome Atlas, consisting of 23 organs and 117 cancer subtypes. As a search platform we used Yottixel that enabled us to perform WSI search using patches. Achieved F1 scores show low performance, e.g., for top-5 retrievals, 27% +/- 13% (Yottixel-DenseNet), 42% +/- 14% (Yottixel-UNI), 40%+/-13% (Yottixel-Virchow), 41%+/-13% (Yottixel-GigaPath), and 41%+/-14% (GigaPath WSI).
format Preprint
id arxiv_https___arxiv_org_abs_2409_04631
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Zero-Shot Whole Slide Image Retrieval in Histopathology Using Embeddings of Foundation Models
Alfasly, Saghir
Alabtah, Ghazal
Hemati, Sobhan
Kalari, Krishna Rani
Tizhoosh, H. R.
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
We have tested recently published foundation models for histopathology for image retrieval. We report macro average of F1 score for top-1 retrieval, majority of top-3 retrievals, and majority of top-5 retrievals. We perform zero-shot retrievals, i.e., we do not alter embeddings and we do not train any classifier. As test data, we used diagnostic slides of TCGA, The Cancer Genome Atlas, consisting of 23 organs and 117 cancer subtypes. As a search platform we used Yottixel that enabled us to perform WSI search using patches. Achieved F1 scores show low performance, e.g., for top-5 retrievals, 27% +/- 13% (Yottixel-DenseNet), 42% +/- 14% (Yottixel-UNI), 40%+/-13% (Yottixel-Virchow), 41%+/-13% (Yottixel-GigaPath), and 41%+/-14% (GigaPath WSI).
title Zero-Shot Whole Slide Image Retrieval in Histopathology Using Embeddings of Foundation Models
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2409.04631