Using Large Language Models to Generate Clinical Trial Tables and Figures

Fuente: arXiv
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Auteurs principaux: Yang, Yumeng, Krusche, Peter, Pantoja, Kristyn, Shi, Cheng, Ludmir, Ethan, Roberts, Kirk, Zhu, Gen
Format: Preprint
Publié: 2024
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author Yang, Yumeng
Krusche, Peter
Pantoja, Kristyn
Shi, Cheng
Ludmir, Ethan
Roberts, Kirk
Zhu, Gen
author_facet Yang, Yumeng
Krusche, Peter
Pantoja, Kristyn
Shi, Cheng
Ludmir, Ethan
Roberts, Kirk
Zhu, Gen
contents Tables, figures, and listings (TFLs) are essential tools for summarizing clinical trial data. Creation of TFLs for reporting activities is often a time-consuming task encountered routinely during the execution of clinical trials. This study explored the use of large language models (LLMs) to automate the generation of TFLs through prompt engineering and few-shot transfer learning. Using public clinical trial data in ADaM format, our results demonstrated that LLMs can efficiently generate TFLs with prompt instructions, showcasing their potential in this domain. Furthermore, we developed a conservational agent named Clinical Trial TFL Generation Agent: An app that matches user queries to predefined prompts that produce customized programs to generate specific predefined TFLs.
format Preprint
id arxiv_https___arxiv_org_abs_2409_12046
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Using Large Language Models to Generate Clinical Trial Tables and Figures
Yang, Yumeng
Krusche, Peter
Pantoja, Kristyn
Shi, Cheng
Ludmir, Ethan
Roberts, Kirk
Zhu, Gen
Computation and Language
Tables, figures, and listings (TFLs) are essential tools for summarizing clinical trial data. Creation of TFLs for reporting activities is often a time-consuming task encountered routinely during the execution of clinical trials. This study explored the use of large language models (LLMs) to automate the generation of TFLs through prompt engineering and few-shot transfer learning. Using public clinical trial data in ADaM format, our results demonstrated that LLMs can efficiently generate TFLs with prompt instructions, showcasing their potential in this domain. Furthermore, we developed a conservational agent named Clinical Trial TFL Generation Agent: An app that matches user queries to predefined prompts that produce customized programs to generate specific predefined TFLs.
title Using Large Language Models to Generate Clinical Trial Tables and Figures
topic Computation and Language
url https://arxiv.org/abs/2409.12046