MambaClinix: Hierarchical Gated Convolution and Mamba-Based U-Net for Enhanced 3D Medical Image Segmentation

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Hauptverfasser: Bian, Chenyuan, Xia, Nan, Yang, Xia, Wang, Feifei, Wang, Fengjiao, Wei, Bin, Dong, Qian
Format: Preprint
Veröffentlicht: 2024
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author Bian, Chenyuan
Xia, Nan
Yang, Xia
Wang, Feifei
Wang, Fengjiao
Wei, Bin
Dong, Qian
author_facet Bian, Chenyuan
Xia, Nan
Yang, Xia
Wang, Feifei
Wang, Fengjiao
Wei, Bin
Dong, Qian
contents Deep learning, particularly convolutional neural networks (CNNs) and Transformers, has significantly advanced 3D medical image segmentation. While CNNs are highly effective at capturing local features, their limited receptive fields may hinder performance in complex clinical scenarios. In contrast, Transformers excel at modeling long-range dependencies but are computationally intensive, making them expensive to train and deploy. Recently, the Mamba architecture, based on the State Space Model (SSM), has been proposed to efficiently model long-range dependencies while maintaining linear computational complexity. However, its application in medical image segmentation reveals shortcomings, particularly in capturing critical local features essential for accurate delineation of clinical regions. In this study, we propose MambaClinix, a novel U-shaped architecture for medical image segmentation that integrates a hierarchical gated convolutional network(HGCN) with Mamba in an adaptive stage-wise framework. This design significantly enhances computational efficiency and high-order spatial interactions, enabling the model to effectively capture both proximal and distal relationships in medical images. Specifically, our HGCN is designed to mimic the attention mechanism of Transformers by a purely convolutional structure, facilitating high-order spatial interactions in feature maps while avoiding the computational complexity typically associated with Transformer-based methods. Additionally, we introduce a region-specific Tversky loss, which emphasizes specific pixel regions to improve auto-segmentation performance, thereby optimizing the model's decision-making process. Experimental results on five benchmark datasets demonstrate that the proposed MambaClinix achieves high segmentation accuracy while maintaining low model complexity.
format Preprint
id arxiv_https___arxiv_org_abs_2409_12533
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle MambaClinix: Hierarchical Gated Convolution and Mamba-Based U-Net for Enhanced 3D Medical Image Segmentation
Bian, Chenyuan
Xia, Nan
Yang, Xia
Wang, Feifei
Wang, Fengjiao
Wei, Bin
Dong, Qian
Image and Video Processing
Computer Vision and Pattern Recognition
Deep learning, particularly convolutional neural networks (CNNs) and Transformers, has significantly advanced 3D medical image segmentation. While CNNs are highly effective at capturing local features, their limited receptive fields may hinder performance in complex clinical scenarios. In contrast, Transformers excel at modeling long-range dependencies but are computationally intensive, making them expensive to train and deploy. Recently, the Mamba architecture, based on the State Space Model (SSM), has been proposed to efficiently model long-range dependencies while maintaining linear computational complexity. However, its application in medical image segmentation reveals shortcomings, particularly in capturing critical local features essential for accurate delineation of clinical regions. In this study, we propose MambaClinix, a novel U-shaped architecture for medical image segmentation that integrates a hierarchical gated convolutional network(HGCN) with Mamba in an adaptive stage-wise framework. This design significantly enhances computational efficiency and high-order spatial interactions, enabling the model to effectively capture both proximal and distal relationships in medical images. Specifically, our HGCN is designed to mimic the attention mechanism of Transformers by a purely convolutional structure, facilitating high-order spatial interactions in feature maps while avoiding the computational complexity typically associated with Transformer-based methods. Additionally, we introduce a region-specific Tversky loss, which emphasizes specific pixel regions to improve auto-segmentation performance, thereby optimizing the model's decision-making process. Experimental results on five benchmark datasets demonstrate that the proposed MambaClinix achieves high segmentation accuracy while maintaining low model complexity.
title MambaClinix: Hierarchical Gated Convolution and Mamba-Based U-Net for Enhanced 3D Medical Image Segmentation
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2409.12533