SelectiveKD: A semi-supervised framework for cancer detection in DBT through Knowledge Distillation and Pseudo-labeling

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Hauptverfasser: Dillard, Laurent, Lee, Hyeonsoo, Lee, Weonsuk, Kim, Tae Soo, Diba, Ali, Kooi, Thijs
Format: Preprint
Veröffentlicht: 2024
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author Dillard, Laurent
Lee, Hyeonsoo
Lee, Weonsuk
Kim, Tae Soo
Diba, Ali
Kooi, Thijs
author_facet Dillard, Laurent
Lee, Hyeonsoo
Lee, Weonsuk
Kim, Tae Soo
Diba, Ali
Kooi, Thijs
contents When developing Computer Aided Detection (CAD) systems for Digital Breast Tomosynthesis (DBT), the complexity arising from the volumetric nature of the modality poses significant technical challenges for obtaining large-scale accurate annotations. Without access to large-scale annotations, the resulting model may not generalize to different domains. Given the costly nature of obtaining DBT annotations, how to effectively increase the amount of data used for training DBT CAD systems remains an open challenge. In this paper, we present SelectiveKD, a semi-supervised learning framework for building cancer detection models for DBT, which only requires a limited number of annotated slices to reach high performance. We achieve this by utilizing unlabeled slices available in a DBT stack through a knowledge distillation framework in which the teacher model provides a supervisory signal to the student model for all slices in the DBT volume. Our framework mitigates the potential noise in the supervisory signal from a sub-optimal teacher by implementing a selective dataset expansion strategy using pseudo labels. We evaluate our approach with a large-scale real-world dataset of over 10,000 DBT exams collected from multiple device manufacturers and locations. The resulting SelectiveKD process effectively utilizes unannotated slices from a DBT stack, leading to significantly improved cancer classification performance (AUC) and generalization performance.
format Preprint
id arxiv_https___arxiv_org_abs_2409_16581
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle SelectiveKD: A semi-supervised framework for cancer detection in DBT through Knowledge Distillation and Pseudo-labeling
Dillard, Laurent
Lee, Hyeonsoo
Lee, Weonsuk
Kim, Tae Soo
Diba, Ali
Kooi, Thijs
Computer Vision and Pattern Recognition
68T45, 92C55 68T45, 92C55
I.4.9; I.5.4
When developing Computer Aided Detection (CAD) systems for Digital Breast Tomosynthesis (DBT), the complexity arising from the volumetric nature of the modality poses significant technical challenges for obtaining large-scale accurate annotations. Without access to large-scale annotations, the resulting model may not generalize to different domains. Given the costly nature of obtaining DBT annotations, how to effectively increase the amount of data used for training DBT CAD systems remains an open challenge. In this paper, we present SelectiveKD, a semi-supervised learning framework for building cancer detection models for DBT, which only requires a limited number of annotated slices to reach high performance. We achieve this by utilizing unlabeled slices available in a DBT stack through a knowledge distillation framework in which the teacher model provides a supervisory signal to the student model for all slices in the DBT volume. Our framework mitigates the potential noise in the supervisory signal from a sub-optimal teacher by implementing a selective dataset expansion strategy using pseudo labels. We evaluate our approach with a large-scale real-world dataset of over 10,000 DBT exams collected from multiple device manufacturers and locations. The resulting SelectiveKD process effectively utilizes unannotated slices from a DBT stack, leading to significantly improved cancer classification performance (AUC) and generalization performance.
title SelectiveKD: A semi-supervised framework for cancer detection in DBT through Knowledge Distillation and Pseudo-labeling
topic Computer Vision and Pattern Recognition
68T45, 92C55 68T45, 92C55
I.4.9; I.5.4
url https://arxiv.org/abs/2409.16581