PNR: Physics-informed Neural Representation for high-resolution LFM reconstruction

Fuente: arXiv
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Autori principali: Zhao, Jiayin, Zhao, Zhifeng, Wu, Jiamin, Yu, Tao, Qiao, Hui
Natura: Preprint
Pubblicazione: 2024
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author Zhao, Jiayin
Zhao, Zhifeng
Wu, Jiamin
Yu, Tao
Qiao, Hui
author_facet Zhao, Jiayin
Zhao, Zhifeng
Wu, Jiamin
Yu, Tao
Qiao, Hui
contents Light field microscopy (LFM) has been widely utilized in various fields for its capability to efficiently capture high-resolution 3D scenes. Despite the rapid advancements in neural representations, there are few methods specifically tailored for microscopic scenes. Existing approaches often do not adequately address issues such as the loss of high-frequency information due to defocus and sample aberration, resulting in suboptimal performance. In addition, existing methods, including RLD, INR, and supervised U-Net, face challenges such as sensitivity to initial estimates, reliance on extensive labeled data, and low computational efficiency, all of which significantly diminish the practicality in complex biological scenarios. This paper introduces PNR (Physics-informed Neural Representation), a method for high-resolution LFM reconstruction that significantly enhances performance. Our method incorporates an unsupervised and explicit feature representation approach, resulting in a 6.1 dB improvement in PSNR than RLD. Additionally, our method employs a frequency-based training loss, enabling better recovery of high-frequency details, which leads to a reduction in LPIPS by at least half compared to SOTA methods (1.762 V.S. 3.646 of DINER). Moreover, PNR integrates a physics-informed aberration correction strategy that optimizes Zernike polynomial parameters during optimization, thereby reducing the information loss caused by aberrations and improving spatial resolution. These advancements make PNR a promising solution for long-term high-resolution biological imaging applications. Our code and dataset will be made publicly available.
format Preprint
id arxiv_https___arxiv_org_abs_2409_18223
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle PNR: Physics-informed Neural Representation for high-resolution LFM reconstruction
Zhao, Jiayin
Zhao, Zhifeng
Wu, Jiamin
Yu, Tao
Qiao, Hui
Image and Video Processing
Computer Vision and Pattern Recognition
Light field microscopy (LFM) has been widely utilized in various fields for its capability to efficiently capture high-resolution 3D scenes. Despite the rapid advancements in neural representations, there are few methods specifically tailored for microscopic scenes. Existing approaches often do not adequately address issues such as the loss of high-frequency information due to defocus and sample aberration, resulting in suboptimal performance. In addition, existing methods, including RLD, INR, and supervised U-Net, face challenges such as sensitivity to initial estimates, reliance on extensive labeled data, and low computational efficiency, all of which significantly diminish the practicality in complex biological scenarios. This paper introduces PNR (Physics-informed Neural Representation), a method for high-resolution LFM reconstruction that significantly enhances performance. Our method incorporates an unsupervised and explicit feature representation approach, resulting in a 6.1 dB improvement in PSNR than RLD. Additionally, our method employs a frequency-based training loss, enabling better recovery of high-frequency details, which leads to a reduction in LPIPS by at least half compared to SOTA methods (1.762 V.S. 3.646 of DINER). Moreover, PNR integrates a physics-informed aberration correction strategy that optimizes Zernike polynomial parameters during optimization, thereby reducing the information loss caused by aberrations and improving spatial resolution. These advancements make PNR a promising solution for long-term high-resolution biological imaging applications. Our code and dataset will be made publicly available.
title PNR: Physics-informed Neural Representation for high-resolution LFM reconstruction
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2409.18223