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Bibliographic Details
Main Authors: Song, Anthony A., Chen, Mason T., Bobrow, Taylor L., Durr, Nicholas J.
Format: Preprint
Published: 2024
Subjects:
Online Access:https://arxiv.org/abs/2409.19153
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author Song, Anthony A.
Chen, Mason T.
Bobrow, Taylor L.
Durr, Nicholas J.
author_facet Song, Anthony A.
Chen, Mason T.
Bobrow, Taylor L.
Durr, Nicholas J.
contents We introduce a compact, two-camera laparoscope that combines active stereo depth estimation and speckle-illumination spatial frequency domain imaging (si-SFDI) to map profile-corrected, pixel-level absorption and reduced scattering optical properties in tissues with complex geometries. Our approach uses multimode fiber-coupled laser illumination to generate high-contrast speckle patterns, requiring only two images for optical property estimation. We demonstrate 3D profilometry using active stereo from low-coherence RGB laser flood illumination, which corrects for measured intensity variations caused by object height and surface angle differences. Validation against conventional SFDI in phantoms and an in-vivo human finger study showed good agreement, with profile-correction improving accuracy for complex geometries. This stereo-laparoscopic implementation of si-SFDI provides a simple method to obtain accurate optical property maps through a laparoscope, potentially offering quantitative endogenous contrast for minimally invasive surgical guidance.
format Preprint
id arxiv_https___arxiv_org_abs_2409_19153
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Speckle-illumination spatial frequency domain imaging with a stereo laparoscope for profile-corrected optical property mapping
Song, Anthony A.
Chen, Mason T.
Bobrow, Taylor L.
Durr, Nicholas J.
Optics
We introduce a compact, two-camera laparoscope that combines active stereo depth estimation and speckle-illumination spatial frequency domain imaging (si-SFDI) to map profile-corrected, pixel-level absorption and reduced scattering optical properties in tissues with complex geometries. Our approach uses multimode fiber-coupled laser illumination to generate high-contrast speckle patterns, requiring only two images for optical property estimation. We demonstrate 3D profilometry using active stereo from low-coherence RGB laser flood illumination, which corrects for measured intensity variations caused by object height and surface angle differences. Validation against conventional SFDI in phantoms and an in-vivo human finger study showed good agreement, with profile-correction improving accuracy for complex geometries. This stereo-laparoscopic implementation of si-SFDI provides a simple method to obtain accurate optical property maps through a laparoscope, potentially offering quantitative endogenous contrast for minimally invasive surgical guidance.
title Speckle-illumination spatial frequency domain imaging with a stereo laparoscope for profile-corrected optical property mapping
topic Optics
url https://arxiv.org/abs/2409.19153