Brain Tumor Classification on MRI in Light of Molecular Markers

Fuente: arXiv
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Autori principali: Liu, Jun, Yuan, Geng, Zeng, Weihao, Tang, Hao, Zhang, Wenbin, Lin, Xue, Xu, XiaoLin, Huang, Dong, Wang, Yanzhi
Natura: Preprint
Pubblicazione: 2024
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author Liu, Jun
Yuan, Geng
Zeng, Weihao
Tang, Hao
Zhang, Wenbin
Lin, Xue
Xu, XiaoLin
Huang, Dong
Wang, Yanzhi
author_facet Liu, Jun
Yuan, Geng
Zeng, Weihao
Tang, Hao
Zhang, Wenbin
Lin, Xue
Xu, XiaoLin
Huang, Dong
Wang, Yanzhi
contents In research findings, co-deletion of the 1p/19q gene is associated with clinical outcomes in low-grade gliomas. The ability to predict 1p19q status is critical for treatment planning and patient follow-up. This study aims to utilize a specially MRI-based convolutional neural network for brain cancer detection. Although public networks such as RestNet and AlexNet can effectively diagnose brain cancers using transfer learning, the model includes quite a few weights that have nothing to do with medical images. As a result, the diagnostic results are unreliable by the transfer learning model. To deal with the problem of trustworthiness, we create the model from the ground up, rather than depending on a pre-trained model. To enable flexibility, we combined convolution stacking with a dropout and full connect operation, it improved performance by reducing overfitting. During model training, we also supplement the given dataset and inject Gaussian noise. We use three--fold cross-validation to train the best selection model. Comparing InceptionV3, VGG16, and MobileNetV2 fine-tuned with pre-trained models, our model produces better results. On an validation set of 125 codeletion vs. 31 not codeletion images, the proposed network achieves 96.37\% percent F1-score, 97.46\% percent precision, and 96.34\% percent recall when classifying 1p/19q codeletion and not codeletion images.
format Preprint
id arxiv_https___arxiv_org_abs_2409_19583
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Brain Tumor Classification on MRI in Light of Molecular Markers
Liu, Jun
Yuan, Geng
Zeng, Weihao
Tang, Hao
Zhang, Wenbin
Lin, Xue
Xu, XiaoLin
Huang, Dong
Wang, Yanzhi
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Quantitative Methods
In research findings, co-deletion of the 1p/19q gene is associated with clinical outcomes in low-grade gliomas. The ability to predict 1p19q status is critical for treatment planning and patient follow-up. This study aims to utilize a specially MRI-based convolutional neural network for brain cancer detection. Although public networks such as RestNet and AlexNet can effectively diagnose brain cancers using transfer learning, the model includes quite a few weights that have nothing to do with medical images. As a result, the diagnostic results are unreliable by the transfer learning model. To deal with the problem of trustworthiness, we create the model from the ground up, rather than depending on a pre-trained model. To enable flexibility, we combined convolution stacking with a dropout and full connect operation, it improved performance by reducing overfitting. During model training, we also supplement the given dataset and inject Gaussian noise. We use three--fold cross-validation to train the best selection model. Comparing InceptionV3, VGG16, and MobileNetV2 fine-tuned with pre-trained models, our model produces better results. On an validation set of 125 codeletion vs. 31 not codeletion images, the proposed network achieves 96.37\% percent F1-score, 97.46\% percent precision, and 96.34\% percent recall when classifying 1p/19q codeletion and not codeletion images.
title Brain Tumor Classification on MRI in Light of Molecular Markers
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Quantitative Methods
url https://arxiv.org/abs/2409.19583