RadGazeGen: Radiomics and Gaze-guided Medical Image Generation using Diffusion Models

Fuente: arXiv
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Autores principales: Bhattacharya, Moinak, Singh, Gagandeep, Jain, Shubham, Prasanna, Prateek
Formato: Preprint
Publicado: 2024
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author Bhattacharya, Moinak
Singh, Gagandeep
Jain, Shubham
Prasanna, Prateek
author_facet Bhattacharya, Moinak
Singh, Gagandeep
Jain, Shubham
Prasanna, Prateek
contents In this work, we present RadGazeGen, a novel framework for integrating experts' eye gaze patterns and radiomic feature maps as controls to text-to-image diffusion models for high fidelity medical image generation. Despite the recent success of text-to-image diffusion models, text descriptions are often found to be inadequate and fail to convey detailed disease-specific information to these models to generate clinically accurate images. The anatomy, disease texture patterns, and location of the disease are extremely important to generate realistic images; moreover the fidelity of image generation can have significant implications in downstream tasks involving disease diagnosis or treatment repose assessment. Hence, there is a growing need to carefully define the controls used in diffusion models for medical image generation. Eye gaze patterns of radiologists are important visuo-cognitive information, indicative of subtle disease patterns and spatial location. Radiomic features further provide important subvisual cues regarding disease phenotype. In this work, we propose to use these gaze patterns in combination with standard radiomics descriptors, as controls, to generate anatomically correct and disease-aware medical images. RadGazeGen is evaluated for image generation quality and diversity on the REFLACX dataset. To demonstrate clinical applicability, we also show classification performance on the generated images from the CheXpert test set (n=500) and long-tailed learning performance on the MIMIC-CXR-LT test set (n=23550).
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id arxiv_https___arxiv_org_abs_2410_00307
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle RadGazeGen: Radiomics and Gaze-guided Medical Image Generation using Diffusion Models
Bhattacharya, Moinak
Singh, Gagandeep
Jain, Shubham
Prasanna, Prateek
Computer Vision and Pattern Recognition
In this work, we present RadGazeGen, a novel framework for integrating experts' eye gaze patterns and radiomic feature maps as controls to text-to-image diffusion models for high fidelity medical image generation. Despite the recent success of text-to-image diffusion models, text descriptions are often found to be inadequate and fail to convey detailed disease-specific information to these models to generate clinically accurate images. The anatomy, disease texture patterns, and location of the disease are extremely important to generate realistic images; moreover the fidelity of image generation can have significant implications in downstream tasks involving disease diagnosis or treatment repose assessment. Hence, there is a growing need to carefully define the controls used in diffusion models for medical image generation. Eye gaze patterns of radiologists are important visuo-cognitive information, indicative of subtle disease patterns and spatial location. Radiomic features further provide important subvisual cues regarding disease phenotype. In this work, we propose to use these gaze patterns in combination with standard radiomics descriptors, as controls, to generate anatomically correct and disease-aware medical images. RadGazeGen is evaluated for image generation quality and diversity on the REFLACX dataset. To demonstrate clinical applicability, we also show classification performance on the generated images from the CheXpert test set (n=500) and long-tailed learning performance on the MIMIC-CXR-LT test set (n=23550).
title RadGazeGen: Radiomics and Gaze-guided Medical Image Generation using Diffusion Models
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2410.00307