Understanding implementation pitfalls of distance-based metrics for image segmentation

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Auteurs principaux: Podobnik, Gasper, Vrtovec, Tomaz
Format: Preprint
Publié: 2024
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author Podobnik, Gasper
Vrtovec, Tomaz
author_facet Podobnik, Gasper
Vrtovec, Tomaz
contents Distance-based metrics, such as the Hausdorff distance (HD), are widely used to validate segmentation performance in (bio)medical imaging. However, their implementation is complex, and critical differences across open-source tools remain largely unrecognized by the community. These discrepancies undermine benchmarking efforts, introduce bias in biomarker calculations, and potentially distort medical device development and clinical commissioning. In this study, we systematically dissect 11 open-source tools that implement distance-based metric computation by performing both a conceptual analysis of their computational steps and an empirical analysis on representative two- and three-dimensional image datasets. Alarmingly, we observed deviations in HD exceeding 100 mm and identified multiple statistically significant differences between tools - demonstrating that statistically significant improvements on the same set of segmentations can be achieved simply by selecting a particular implementation. These findings cast doubts on the validity of prior comparisons of results across studies without accounting for the differences in metric implementations. To address this, we provide practical recommendations for tool selection; additionally, our conceptual analysis informs about the future evolution of implementing open-source tools.
format Preprint
id arxiv_https___arxiv_org_abs_2410_02630
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Understanding implementation pitfalls of distance-based metrics for image segmentation
Podobnik, Gasper
Vrtovec, Tomaz
Computer Vision and Pattern Recognition
Distance-based metrics, such as the Hausdorff distance (HD), are widely used to validate segmentation performance in (bio)medical imaging. However, their implementation is complex, and critical differences across open-source tools remain largely unrecognized by the community. These discrepancies undermine benchmarking efforts, introduce bias in biomarker calculations, and potentially distort medical device development and clinical commissioning. In this study, we systematically dissect 11 open-source tools that implement distance-based metric computation by performing both a conceptual analysis of their computational steps and an empirical analysis on representative two- and three-dimensional image datasets. Alarmingly, we observed deviations in HD exceeding 100 mm and identified multiple statistically significant differences between tools - demonstrating that statistically significant improvements on the same set of segmentations can be achieved simply by selecting a particular implementation. These findings cast doubts on the validity of prior comparisons of results across studies without accounting for the differences in metric implementations. To address this, we provide practical recommendations for tool selection; additionally, our conceptual analysis informs about the future evolution of implementing open-source tools.
title Understanding implementation pitfalls of distance-based metrics for image segmentation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2410.02630