Diagnosis of Malignant Lymphoma Cancer Using Hybrid Optimized Techniques Based on Dense Neural Networks

Fuente: arXiv
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Autores principales: Aly, Salah A., Bakhiet, Ali, Balat, Mazen
Formato: Preprint
Publicado: 2024
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author Aly, Salah A.
Bakhiet, Ali
Balat, Mazen
author_facet Aly, Salah A.
Bakhiet, Ali
Balat, Mazen
contents Lymphoma diagnosis, particularly distinguishing between subtypes, is critical for effective treatment but remains challenging due to the subtle morphological differences in histopathological images. This study presents a novel hybrid deep learning framework that combines DenseNet201 for feature extraction with a Dense Neural Network (DNN) for classification, optimized using the Harris Hawks Optimization (HHO) algorithm. The model was trained on a dataset of 15,000 biopsy images, spanning three lymphoma subtypes: Chronic Lymphocytic Leukemia (CLL), Follicular Lymphoma (FL), and Mantle Cell Lymphoma (MCL). Our approach achieved a testing accuracy of 99.33\%, demonstrating significant improvements in both accuracy and model interpretability. Comprehensive evaluation using precision, recall, F1-score, and ROC-AUC underscores the model's robustness and potential for clinical adoption. This framework offers a scalable solution for improving diagnostic accuracy and efficiency in oncology.
format Preprint
id arxiv_https___arxiv_org_abs_2410_06974
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Diagnosis of Malignant Lymphoma Cancer Using Hybrid Optimized Techniques Based on Dense Neural Networks
Aly, Salah A.
Bakhiet, Ali
Balat, Mazen
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Lymphoma diagnosis, particularly distinguishing between subtypes, is critical for effective treatment but remains challenging due to the subtle morphological differences in histopathological images. This study presents a novel hybrid deep learning framework that combines DenseNet201 for feature extraction with a Dense Neural Network (DNN) for classification, optimized using the Harris Hawks Optimization (HHO) algorithm. The model was trained on a dataset of 15,000 biopsy images, spanning three lymphoma subtypes: Chronic Lymphocytic Leukemia (CLL), Follicular Lymphoma (FL), and Mantle Cell Lymphoma (MCL). Our approach achieved a testing accuracy of 99.33\%, demonstrating significant improvements in both accuracy and model interpretability. Comprehensive evaluation using precision, recall, F1-score, and ROC-AUC underscores the model's robustness and potential for clinical adoption. This framework offers a scalable solution for improving diagnostic accuracy and efficiency in oncology.
title Diagnosis of Malignant Lymphoma Cancer Using Hybrid Optimized Techniques Based on Dense Neural Networks
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2410.06974