Exact MLE for Generalized Linear Mixed Models

Fuente: arXiv
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1. Verfasser: Zhang, Tonglin
Format: Preprint
Veröffentlicht: 2024
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_version_ 1866916433529667584
author Zhang, Tonglin
author_facet Zhang, Tonglin
contents Exact MLE for generalized linear mixed models (GLMMs) is a long-standing problem unsolved until today. The proposed research solves the problem. In this problem, the main difficulty is caused by intractable integrals in the likelihood function when the response does not follow normal and the prior distribution for the random effects is specified by normal. Previous methods use Laplace approximations or Monte Carol simulations to compute the MLE approximately. These methods cannot provide the exact MLEs of the parameters and the hyperparameters. The exact MLE problem remains unsolved until the proposed work. The idea is to construct a sequence of mathematical functions in the optimization procedure. Optimization of the mathematical functions can be numerically computed. The result can lead to the exact MLEs of the parameters and hyperparameters. Because computing the likelihood is unnecessary, the proposed method avoids the main difficulty caused by the intractable integrals in the likelihood function.
format Preprint
id arxiv_https___arxiv_org_abs_2410_08492
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Exact MLE for Generalized Linear Mixed Models
Zhang, Tonglin
Methodology
62F15, 62J05, 62J12
Exact MLE for generalized linear mixed models (GLMMs) is a long-standing problem unsolved until today. The proposed research solves the problem. In this problem, the main difficulty is caused by intractable integrals in the likelihood function when the response does not follow normal and the prior distribution for the random effects is specified by normal. Previous methods use Laplace approximations or Monte Carol simulations to compute the MLE approximately. These methods cannot provide the exact MLEs of the parameters and the hyperparameters. The exact MLE problem remains unsolved until the proposed work. The idea is to construct a sequence of mathematical functions in the optimization procedure. Optimization of the mathematical functions can be numerically computed. The result can lead to the exact MLEs of the parameters and hyperparameters. Because computing the likelihood is unnecessary, the proposed method avoids the main difficulty caused by the intractable integrals in the likelihood function.
title Exact MLE for Generalized Linear Mixed Models
topic Methodology
62F15, 62J05, 62J12
url https://arxiv.org/abs/2410.08492