Learning Representations of Instruments for Partial Identification of Treatment Effects

Fuente: arXiv
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Main Authors: Schweisthal, Jonas, Frauen, Dennis, Schröder, Maresa, Hess, Konstantin, Kilbertus, Niki, Feuerriegel, Stefan
Format: Preprint
Published: 2024
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_version_ 1866914971250589696
author Schweisthal, Jonas
Frauen, Dennis
Schröder, Maresa
Hess, Konstantin
Kilbertus, Niki
Feuerriegel, Stefan
author_facet Schweisthal, Jonas
Frauen, Dennis
Schröder, Maresa
Hess, Konstantin
Kilbertus, Niki
Feuerriegel, Stefan
contents Reliable estimation of treatment effects from observational data is important in many disciplines such as medicine. However, estimation is challenging when unconfoundedness as a standard assumption in the causal inference literature is violated. In this work, we leverage arbitrary (potentially high-dimensional) instruments to estimate bounds on the conditional average treatment effect (CATE). Our contributions are three-fold: (1) We propose a novel approach for partial identification through a mapping of instruments to a discrete representation space so that we yield valid bounds on the CATE. This is crucial for reliable decision-making in real-world applications. (2) We derive a two-step procedure that learns tight bounds using a tailored neural partitioning of the latent instrument space. As a result, we avoid instability issues due to numerical approximations or adversarial training. Furthermore, our procedure aims to reduce the estimation variance in finite-sample settings to yield more reliable estimates. (3) We show theoretically that our procedure obtains valid bounds while reducing estimation variance. We further perform extensive experiments to demonstrate the effectiveness across various settings. Overall, our procedure offers a novel path for practitioners to make use of potentially high-dimensional instruments (e.g., as in Mendelian randomization).
format Preprint
id arxiv_https___arxiv_org_abs_2410_08976
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Learning Representations of Instruments for Partial Identification of Treatment Effects
Schweisthal, Jonas
Frauen, Dennis
Schröder, Maresa
Hess, Konstantin
Kilbertus, Niki
Feuerriegel, Stefan
Machine Learning
Artificial Intelligence
Reliable estimation of treatment effects from observational data is important in many disciplines such as medicine. However, estimation is challenging when unconfoundedness as a standard assumption in the causal inference literature is violated. In this work, we leverage arbitrary (potentially high-dimensional) instruments to estimate bounds on the conditional average treatment effect (CATE). Our contributions are three-fold: (1) We propose a novel approach for partial identification through a mapping of instruments to a discrete representation space so that we yield valid bounds on the CATE. This is crucial for reliable decision-making in real-world applications. (2) We derive a two-step procedure that learns tight bounds using a tailored neural partitioning of the latent instrument space. As a result, we avoid instability issues due to numerical approximations or adversarial training. Furthermore, our procedure aims to reduce the estimation variance in finite-sample settings to yield more reliable estimates. (3) We show theoretically that our procedure obtains valid bounds while reducing estimation variance. We further perform extensive experiments to demonstrate the effectiveness across various settings. Overall, our procedure offers a novel path for practitioners to make use of potentially high-dimensional instruments (e.g., as in Mendelian randomization).
title Learning Representations of Instruments for Partial Identification of Treatment Effects
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2410.08976