TopOC: Topological Deep Learning for Ovarian and Breast Cancer Diagnosis

Fuente: arXiv
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Autores principales: Fatema, Saba, Nuwagira, Brighton, Chakraborty, Sayoni, Gedik, Reyhan, Coskunuzer, Baris
Formato: Preprint
Publicado: 2024
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author Fatema, Saba
Nuwagira, Brighton
Chakraborty, Sayoni
Gedik, Reyhan
Coskunuzer, Baris
author_facet Fatema, Saba
Nuwagira, Brighton
Chakraborty, Sayoni
Gedik, Reyhan
Coskunuzer, Baris
contents Microscopic examination of slides prepared from tissue samples is the primary tool for detecting and classifying cancerous lesions, a process that is time-consuming and requires the expertise of experienced pathologists. Recent advances in deep learning methods hold significant potential to enhance medical diagnostics and treatment planning by improving accuracy, reproducibility, and speed, thereby reducing clinicians' workloads and turnaround times. However, the necessity for vast amounts of labeled data to train these models remains a major obstacle to the development of effective clinical decision support systems. In this paper, we propose the integration of topological deep learning methods to enhance the accuracy and robustness of existing histopathological image analysis models. Topological data analysis (TDA) offers a unique approach by extracting essential information through the evaluation of topological patterns across different color channels. While deep learning methods capture local information from images, TDA features provide complementary global features. Our experiments on publicly available histopathological datasets demonstrate that the inclusion of topological features significantly improves the differentiation of tumor types in ovarian and breast cancers.
format Preprint
id arxiv_https___arxiv_org_abs_2410_09818
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle TopOC: Topological Deep Learning for Ovarian and Breast Cancer Diagnosis
Fatema, Saba
Nuwagira, Brighton
Chakraborty, Sayoni
Gedik, Reyhan
Coskunuzer, Baris
Computer Vision and Pattern Recognition
Machine Learning
Algebraic Topology
Microscopic examination of slides prepared from tissue samples is the primary tool for detecting and classifying cancerous lesions, a process that is time-consuming and requires the expertise of experienced pathologists. Recent advances in deep learning methods hold significant potential to enhance medical diagnostics and treatment planning by improving accuracy, reproducibility, and speed, thereby reducing clinicians' workloads and turnaround times. However, the necessity for vast amounts of labeled data to train these models remains a major obstacle to the development of effective clinical decision support systems. In this paper, we propose the integration of topological deep learning methods to enhance the accuracy and robustness of existing histopathological image analysis models. Topological data analysis (TDA) offers a unique approach by extracting essential information through the evaluation of topological patterns across different color channels. While deep learning methods capture local information from images, TDA features provide complementary global features. Our experiments on publicly available histopathological datasets demonstrate that the inclusion of topological features significantly improves the differentiation of tumor types in ovarian and breast cancers.
title TopOC: Topological Deep Learning for Ovarian and Breast Cancer Diagnosis
topic Computer Vision and Pattern Recognition
Machine Learning
Algebraic Topology
url https://arxiv.org/abs/2410.09818