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Autori principali: Tozuka, Ryota, Johno, Hisashi, Amakawa, Akitomo, Sato, Junichi, Muto, Mizuki, Seki, Shoichiro, Komaba, Atsushi, Onishi, Hiroshi
Natura: Preprint
Pubblicazione: 2024
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Accesso online:https://arxiv.org/abs/2410.10869
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author Tozuka, Ryota
Johno, Hisashi
Amakawa, Akitomo
Sato, Junichi
Muto, Mizuki
Seki, Shoichiro
Komaba, Atsushi
Onishi, Hiroshi
author_facet Tozuka, Ryota
Johno, Hisashi
Amakawa, Akitomo
Sato, Junichi
Muto, Mizuki
Seki, Shoichiro
Komaba, Atsushi
Onishi, Hiroshi
contents Purpose: In radiology, large language models (LLMs), including ChatGPT, have recently gained attention, and their utility is being rapidly evaluated. However, concerns have emerged regarding their reliability in clinical applications due to limitations such as hallucinations and insufficient referencing. To address these issues, we focus on the latest technology, retrieval-augmented generation (RAG), which enables LLMs to reference reliable external knowledge (REK). Specifically, this study examines the utility and reliability of a recently released RAG-equipped LLM (RAG-LLM), NotebookLM, for staging lung cancer. Materials and methods: We summarized the current lung cancer staging guideline in Japan and provided this as REK to NotebookLM. We then tasked NotebookLM with staging 100 fictional lung cancer cases based on CT findings and evaluated its accuracy. For comparison, we performed the same task using a gold-standard LLM, GPT-4 Omni (GPT-4o), both with and without the REK. Results: NotebookLM achieved 86% diagnostic accuracy in the lung cancer staging experiment, outperforming GPT-4o, which recorded 39% accuracy with the REK and 25% without it. Moreover, NotebookLM demonstrated 95% accuracy in searching reference locations within the REK. Conclusion: NotebookLM successfully performed lung cancer staging by utilizing the REK, demonstrating superior performance compared to GPT-4o. Additionally, it provided highly accurate reference locations within the REK, allowing radiologists to efficiently evaluate the reliability of NotebookLM's responses and detect possible hallucinations. Overall, this study highlights the potential of NotebookLM, a RAG-LLM, in image diagnosis.
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publishDate 2024
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spellingShingle Application of NotebookLM, a Large Language Model with Retrieval-Augmented Generation, for Lung Cancer Staging
Tozuka, Ryota
Johno, Hisashi
Amakawa, Akitomo
Sato, Junichi
Muto, Mizuki
Seki, Shoichiro
Komaba, Atsushi
Onishi, Hiroshi
Computation and Language
Artificial Intelligence
Machine Learning
Purpose: In radiology, large language models (LLMs), including ChatGPT, have recently gained attention, and their utility is being rapidly evaluated. However, concerns have emerged regarding their reliability in clinical applications due to limitations such as hallucinations and insufficient referencing. To address these issues, we focus on the latest technology, retrieval-augmented generation (RAG), which enables LLMs to reference reliable external knowledge (REK). Specifically, this study examines the utility and reliability of a recently released RAG-equipped LLM (RAG-LLM), NotebookLM, for staging lung cancer. Materials and methods: We summarized the current lung cancer staging guideline in Japan and provided this as REK to NotebookLM. We then tasked NotebookLM with staging 100 fictional lung cancer cases based on CT findings and evaluated its accuracy. For comparison, we performed the same task using a gold-standard LLM, GPT-4 Omni (GPT-4o), both with and without the REK. Results: NotebookLM achieved 86% diagnostic accuracy in the lung cancer staging experiment, outperforming GPT-4o, which recorded 39% accuracy with the REK and 25% without it. Moreover, NotebookLM demonstrated 95% accuracy in searching reference locations within the REK. Conclusion: NotebookLM successfully performed lung cancer staging by utilizing the REK, demonstrating superior performance compared to GPT-4o. Additionally, it provided highly accurate reference locations within the REK, allowing radiologists to efficiently evaluate the reliability of NotebookLM's responses and detect possible hallucinations. Overall, this study highlights the potential of NotebookLM, a RAG-LLM, in image diagnosis.
title Application of NotebookLM, a Large Language Model with Retrieval-Augmented Generation, for Lung Cancer Staging
topic Computation and Language
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2410.10869